179548-79-9

Basic information

• Product Name: C₁₅H₁₇ClSn
• Synonyms: C₁₅H₁₇ClSn
• CAS NO: 179548-79-9
• Molecular Weight: 351.463
• Mol File: 179548-79-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₅H₁₇ClSn(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₁₇ClSn(179548-79-9)
• EPA Substance Registry System: C₁₅H₁₇ClSn(179548-79-9)

Safety Data

• Hazardous Substances Data: 179548-79-9(Hazardous Substances Data)

Upstream product

• 23055-77-8 4'-chloro-4-bromo-biphenyl 
• 1066-45-1 trimethyltin(IV)chloride 

Relevant articles and documents

INHIBITION OF MATRIX METALLOPROTEASES BY SUBSTITUTED BIARYL OXOBUTYRIC ACIDS

Matrix metalloprotease inhibiting compounds, pharmaceutical compositions thereof and a method of disease treatment using such compounds are presented. The compounds of the invention have generalized formula (1) wherein r is 0-2, T is selected from (a) and (b) and R is a mono- or bi-heterocyclic structure. These compounds are useful for inhibiting matrix metalloproteases and, therefore, combating conditions to which MMP's contribute, such as osteoarthritis, rheumatoid arthritis, septic arthritis, periodontal disease, corneal ulceration, proteinuria, aneurysmal aortic disease, dystrophobic epidermolysis, bullosa, conditions leading to inflammatory responses, osteopenias mediated by MMP activity, tempero mandibular joint disease, demyelating diseases of the nervous system, tumor metastasis of degenerative cartilage loss following traumatic joint injury, and coronary thrombosis from athrosclerotic plaque rupture. The present invention also provides pharmaceutical compositions and methods for treating such conditions.