179803-80-6Relevant articles and documents
Water-soluble fluorescent polymers that respond to singlet oxygen
Altinok, Esra,Frausto, Fanny,Thomas, Samuel W.
, p. 2526 - 2535 (2016/07/14)
Although acenes with more than three fused rings can both fluoresce efficiently and react with singlet oxygen (1O2) rapidly, their hydrophobic nature presents a challenge to their use in aqueous environments. Herein we report a series of fluorescent, water-soluble random copolymers that each comprise (oligoethylene glycol) methacrylate (OEGMA) and one of several diarylacene methacrylates, including a tetracene methacrylate and a tetraceneothiophene methacrylate. Exposure to 1O2 in water oxidizes the pendant acenes, resulting in diminution of their fluorescence intensities. The observed rate of oxidation of the tetracene-containing polymers compares favorably with a commercial 1O2-sensitive dye. Polymers that also include energy-donating coumarin side chains show ratiometric fluorescence changes in response to 1O2.