18002-03-4

Basic information

• Product Name: 2-benzyl-5,6-tetramethylenethieno<2,3-d>pyrimidin-4(3H)-one
• Synonyms: 2-benzyl-5,6-tetramethylenethieno<2,3-d>pyrimidin-4(3H)-one
• CAS NO: 18002-03-4
• Molecular Weight: 296.393
• Mol File: 18002-03-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-benzyl-5,6-tetramethylenethieno<2,3-d>pyrimidin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzyl-5,6-tetramethylenethieno<2,3-d>pyrimidin-4(3H)-one(18002-03-4)
• EPA Substance Registry System: 2-benzyl-5,6-tetramethylenethieno<2,3-d>pyrimidin-4(3H)-one(18002-03-4)

Safety Data

• Hazardous Substances Data: 18002-03-4(Hazardous Substances Data)

Upstream product

• 4506-71-2 ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 
• 140-29-4 phenylacetonitrile 
• 122-78-1 phenylacetaldehyde 
• 4815-28-5 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide 
• 108-94-1 cyclohexanone 
• 103-81-1 Benzeneacetamide 
• 76488-06-7 Ethyl 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate-hydrochloride 
• 645-54-5 2-phenylthioacetamide 
• 101-97-3 Ethyl 2-phenylethanoate 
• 4971-77-1 ethyl 2-phenylethanimidoate 

Downstream Products

• 401511-15-7 2-benzyl-4-[(2-hydroxy)ethyl]amino-5,6,7,8-tetrahydrobenzo(b)thieno[2,3-d]pyrimidine 
• 423128-56-7 2-benzyl-4-(4-methylpiperazin-1-yl)-5,6,7,8-tetrahydrobenzo[4,5]-thieno[2,3-d]pyrimidine 
• 83548-64-5 (2-Benzyl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazine 
• 83548-71-4 4-Benzyl-7,8,9,10-tetrahydro-6-thia-1,2,3,3a,5-pentaaza-cyclopenta[c]fluorene 
• 947328-95-2 2-benzyl-4-[(3-hydroxy)propyl]amino-5,6,7,8-tetrahydrobenzo[b]thieno[2,3-d]pyrimidine 
• 83548-57-6 2-Benzyl-4-chloro-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine 

Relevant articles and documents

Antihelminthic activity of some 2-substituted thieno[2,3-d]pyrimidin-4-ones

Background: One of the successful approaches for rational design of bioactive compounds is the bioisosterism strategy. Thus, the bioisosteric relation of thieno[2,3-d]pyrimidin-4-ones with quinazolines, cytosine and uracil resulted in the generation of co

Microwave-assisted synthesis of potent PDE7 inhibitors containing a thienopyrimidin-4-amine scaffold

A series of novel thienopyrimidin-4-amines have been synthesized and evaluated as phosphodiesterase (PDE) inhibitors. A rationale for the observed selectivity against PDE7 has been obtained from molecular modelling studies on the most active compounds. This journal is the Partner Organisations 2014.

Microwave-Assisted Synthesis of Novel 5-Substituted-2,3-dihydroimidazo[1,2-c]thieno[3,2-e]pyrimidines

A novel, facile microwave-assisted route for the synthesis of imidazo[1,2-c]thieno[3,2-e]pyrimidines 4 in quantitative yields is reported. The intermediates 4-chlorothieno[2,3-d]pyrimidines 3 were synthesized under one-pot reaction conditions.