180078-11-9

Basic information

• Product Name: (S)-2-tert-Butoxycarbonylamino-3-(4-ethoxycarbonylmethoxy-phenyl)-propionic acid
• Synonyms: (S)-2-tert-Butoxycarbonylamino-3-(4-ethoxycarbonylmethoxy-phenyl)-propionic acid
• CAS NO: 180078-11-9
• Molecular Weight: 367.399
• Mol File: 180078-11-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-2-tert-Butoxycarbonylamino-3-(4-ethoxycarbonylmethoxy-phenyl)-propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-tert-Butoxycarbonylamino-3-(4-ethoxycarbonylmethoxy-phenyl)-propionic acid(180078-11-9)
• EPA Substance Registry System: (S)-2-tert-Butoxycarbonylamino-3-(4-ethoxycarbonylmethoxy-phenyl)-propionic acid(180078-11-9)

Safety Data

• Hazardous Substances Data: 180078-11-9(Hazardous Substances Data)

Upstream product

• 19391-35-6 N-tert-butoxycarbonyl-L-tyrosine benzyl ester 
• 3978-80-1 Boc-Tyr-OH 
• 105-39-5 chloroacetic acid ethyl ester 

Relevant articles and documents

Discovery and SAR of novel, potent and selective protein tyrosine phosphatase 1B inhibitors

A salicylate second site binder was linked to three classes of phosphotyrosine mimetics to produce potent protein tyrosine phosphatase 1B (PTP1B) inhibitors which exhibit significant selectivity against other phosphatases including the most homologous mem

Structure-activity relationships for macrocyclic peptidomimetic inhibitors of HIV-1 protease

A series of appended macrocycles were synthesized and tested as inhibitors of HIV-1 protease (HIV PR). The macrocycle structurally mimics an N-terminal tripeptide component of peptide substrates. Structure-activity relationships explore steric limitations to the size and shape of the substituents and provide evidence for functional mimicry of substrate components.