180143-70-8Relevant articles and documents
Guanidinium and Amidinium Fungicides: A New Class of Crbocation Mimetic Ergosterol Biosynthesis Inhibitors
Arnold, Mary L.,Duriatti, Albert D.,Jung, Michel,Katz, Ruth B.,Liebeschuetz, John W.
, p. 341 - 356 (2007/10/03)
A novel class of chemical has been designed with the aim of inhibiting the Δ14-reductase and Δ8-Δ7-isomerase enzymes in the ergosterol biosynthesis pathway in fungi. Use was made of knowledge about the mechanisms of both e