180150-75-8

Basic information

• Product Name: Carbamic acid, [(ethylamino)thioxomethyl]-, 1,1-dimethylethyl ester (9CI)
• Synonyms: Carbamic acid, [(ethylamino)thioxomethyl]-, 1,1-dimethylethyl ester (9CI)
• CAS NO: 180150-75-8
• Molecular Formula: C₈H₁₆N₂O₂S
• Molecular Weight: 204.28984
• Product Categories: N-BOC
• Mol File: 180150-75-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Carbamic acid, [(ethylamino)thioxomethyl]-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(ethylamino)thioxomethyl]-, 1,1-dimethylethyl ester (9CI)(180150-75-8)
• EPA Substance Registry System: Carbamic acid, [(ethylamino)thioxomethyl]-, 1,1-dimethylethyl ester (9CI)(180150-75-8)

Safety Data

• Hazardous Substances Data: 180150-75-8(Hazardous Substances Data)

Upstream product

• 542-85-8 Ethyl isothiocyanate 
• 4248-19-5 tert-butyl carbazate 

Downstream Products

• 1262799-46-1 tert-butyl ((4aS,5S,7aS)-3-ethyl-7a-(2-fluorophenyl)-4-oxo-5-(trifluoromethyl)-3,4,4a,5,7,7a-hexahydrofuro[3,4-d]pyrimidin-2-yl)carbamate 

Relevant articles and documents

IMINOTETRAHYDROPYRIMIDINONE DERIVATIVES AS PLASMEPSIN V INHIBITORS

A series of 2-imino-6-methyltetrahydropyrimidin-4(lH)-one derivatives, substituted in the 6-position by a phenyl moiety which in turn is meta-substituted by an optionally substituted unsaturated fused bicyclic ring system containing at least one nitrogen atom, being selective inhibitors of plasmepsin V activity, are beneficial as pharmaceutical agents, especially in the treatment of malaria.

DIHYDROPYRIMIDINONES FOR USE AS BACE2 INHIBITORS

This invention relates to dihydropyrimidinones of the formula (I), wherein X and R1 to R7 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are BACE2 inhibitors