180258-99-5

Basic information

• Product Name: 1-(1-adamantyl)cyclopentanamine
• CAS NO: 180258-99-5
• Molecular Weight: 219.37
• Mol File: 180258-99-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(1-adamantyl)cyclopentanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-adamantyl)cyclopentanamine(180258-99-5)
• EPA Substance Registry System: 1-(1-adamantyl)cyclopentanamine(180258-99-5)

Safety Data

• Hazardous Substances Data: 180258-99-5(Hazardous Substances Data)

Upstream product

• 137506-88-8 1-(1-adamantyl)cyclopentanol 
• 2094-73-7 ethyl 1-adamantanecarboxylate 

Relevant articles and documents

Synthesis and pharmacological study of some adamantylcyclopentanamines

In this paper the synthesis of adamantylcyclopentanamines 5, 7 and 8 is described. The experimental data obtained with these derivatives on mice (behaviour, effect on the reserpinic catalepsy or hypothermy, study of the convulsions obtained with high doses) argue in favour of the existence of a glutamatergic component on the action mechanism of these adamantanamines.

Binding and Proton Blockage by Amantadine Variants of the Influenza M2WT and M2S31N Explained

While aminoadamantanes are well-established inhibitors of the influenza A M2 proton channel, the mechanisms by which they are rendered ineffective against M2S31N are unclear. Solid state NMR, isothermal titration calorimetry, electrophysiology,