180272-28-0

Basic information

• Product Name: Solifenacin N-Oxide
• Synonyms: (1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid (3R)-1-Oxido-1-azabicyclo[2.2.2]oct-3-yl Ester;Solifenacin N-Oxide;(1R,3R,4R)-3-((1-phenyl-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)oxy)quinuclidine 1-oxide;Solifenacin Impurity I;Solifenacin EP Impurity I;(R)-3-(((S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)oxy)quinuclidine 1-oxide
• CAS NO: 180272-28-0
• Molecular Formula: C₂₃H₂₆N₂O₃
• Molecular Weight: 378.46
• Product Categories: Chiral Reagents;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
• Mol File: 180272-28-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer
• Solubility: DMSO (Slightly, Heated), Methanol (Slightly)
• Stability: Very Hygroscopic
• CAS DataBase Reference: Solifenacin N-Oxide(CAS DataBase Reference)
• NIST Chemistry Reference: Solifenacin N-Oxide(180272-28-0)
• EPA Substance Registry System: Solifenacin N-Oxide(180272-28-0)

Safety Data

• Hazardous Substances Data: 180272-28-0(Hazardous Substances Data)

Usage

Chemical Properties

White Low-Melting Solid

Uses

A metabolite of Solifenacin (S676700) .

InChI:InChI=1/C23H26N2O3/c26-23(28-21-16-25(27)14-11-18(21)12-15-25)24-13-10-17-6-4-5-9-20(17)22(24)19-7-2-1-3-8-19/h1-9,18,21-22H,10-16H2/t18?,21-,22?,25?/m0/s1

Upstream product

• 242478-37-1 solifenacin 

Relevant articles and documents

A PROCESS FOR THE PREPARATION OF SOLIFENACIN OR A SALT THEREOF

The present invention relates to an improved process for the preparation of Solifenacin or its salt of formula I, more particularly the present invention relates to an economically viable and industrially advantageous process for the preparation of highly pure Solifenacin or its salt of formula I.