1806-66-2

Basic information

• Product Name: Quinazoline, 4-methyl-2-phenyl-
• CAS NO: 1806-66-2
• Molecular Formula: C15H12N2
• Molecular Weight: 220.274
• Mol File: 1806-66-2.mol
• Article Data: 35

Chemical Properties

• CAS DataBase Reference: Quinazoline, 4-methyl-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Quinazoline, 4-methyl-2-phenyl-(1806-66-2)
• EPA Substance Registry System: Quinazoline, 4-methyl-2-phenyl-(1806-66-2)

Safety Data

• Hazardous Substances Data: 1806-66-2(Hazardous Substances Data)

Upstream product

• 6011-26-3 2'-acetylbenzanilide 
• 1644428-63-6 N-[2-(1-azidoethyl)phenyl]formamide 
• 1644428-71-6 1-(1-azidoethyl)-2-isocyanobenzene 
• 98-80-6 phenylboronic acid 
• 106795-49-7 N-[2-(1-hydroxyethyl)phenyl]formamide 
• 941706-81-6 1-(2-aminophenyl)ethanol 
• 872-36-6 vinylene carbonate 
• 1313761-07-7 N-(2-deuteriophenyl)benzamidine 
• 1527-91-9 N-phenylbenzamidine 
• 55-21-0 benzamide 
• 103-82-2 phenylacetic acid 
• 80379-10-8 1-(2-nitrophenyl)ethan-1-ol 
• 100-47-0 benzonitrile 
• 551-93-9 2-aminoacetophenone 

Downstream Products

• 1452815-50-7 4-(4-nitrobenzyl)-2-phenylquinazoline 
• 1452815-49-4 (4-nitrophenyl)(2-phenylquinazolin-4-yl)methanone 
• 1591672-49-9 5-phenyl-3-(thiophen-2-yl)imidazo[1,5-c]quinazoline 
• 1591672-47-7 3-(furan-2-yl)-5-phenylimidazo[1,5-c]quinazoline 
• 1591672-45-5 3-(naphthalen-1-yl)-5-phenylimidazo[1,5-c]quinazoline 
• 1591672-43-3 5-phenyl-3-(4-trifluoromethylphenyl)imidazo[1,5-c]quinazoline 
• 1591672-41-1 3-(4-bromophenyl)-5-phenylimidazo[1,5-c]quinazoline 
• 1591672-39-7 3-(4-chlorophenyl)-5-phenylimidazo[1,5-c]quinazoline 
• 1591672-37-5 3-(4-fluorophenyl)-5-phenylimidazo[1,5-c]quinazoline 
• 1591672-35-3 3-(4-methoxyphenyl)-5-phenylimidazo[1,5-c]quinazoline 
• 1591672-33-1 3-(4-tert-butylphenyl)-5-phenylimidazo[1,5-c]quinazoline 
• 1591672-31-9 5-phenyl-3-(p-tolyl)imidazo[1,5-c]quinazoline 
• 1591672-29-5 5-phenyl-3-(m-tolyl)imidazo[1,5-c]quinazoline 
• 1591672-27-3 5-phenyl-3-(o-tolyl)imidazo[1,5-c]quinazoline 

Relevant articles and documents

Mn(iii)-mediated cascade cyclization of 1-(azidomethyl)-2-isocyanoarenes with organoboronic acids: Construction of quinazoline derivatives

A novel and efficient Mn(iii)-mediated oxidative radical cascade reaction of 1-(azidomethyl)-2-isocyanoarenes with organoboronic acids is reported. The single electron oxidation of a commercially available organo boronic acid in the presence of a mild oxidant, Mn(OAc)3·2H2O, resulted in moderate yields of the corresponding quinazoline derivatives.

Efficient synthesis of quinazolines by the iron-catalyzed acceptorless dehydrogenative coupling of (2-aminophenyl)methanols and benzamides

The acceptorless dehydrogenation coupling (ADC) of (2-aminophenyl)methanols with benzamides was achieved with catalytic FeCl2·4H2O in an efficient synthesis of quinazolines. This simple catalytic system is atom-economical, environmentally benign and suited to a variety of substrates.

Hydrogen peroxide-mediated synthesis of 2,4-substituted quinazolines: Via one-pot three-component reactions under metal-free conditions

An efficient metal-free synthesis of 2,4-substituted quinazolines via a hydrogen peroxide-mediated one-pot three-component reaction of 2-aminoaryl ketones, aldehydes, and ammonium acetate has been developed. The transformation proceeded readily under mild conditions in the presence of commercially available hydrogen peroxide. The significant advantages of this approach are (1) the readily available atom-efficient and green hydrogen peroxide as oxidant; (2) no transition metal catalyst is required; (3) mild reaction conditions; and (4) wide substrate scope. To the best of our knowledge, utilizing hydrogen peroxide as an atom-efficient and green oxidant for the synthesis of 2,4-substituted quinazolines has not previously been reported in the literature. This method is complementary to previous protocols for the synthesis of 2,4-substituted quinazolines. This journal is