18068-82-1

Basic information

• Product Name: 2-Phenylfuro[3,2-b]pyridine
• Synonyms: 2-Phenylfuro[3,2-b]pyridine;Furo[3,2-b]pyridine,2-phenyl-(8CI,9CI)
• CAS NO: 18068-82-1
• Molecular Formula: C₁₃H₉NO
• Molecular Weight: 195.21666
• Product Categories: PYRIDINE
• Mol File: 18068-82-1.mol
• Article Data: 15

Chemical Properties

• Melting Point: 89-91℃
• Appearance: /
• CAS DataBase Reference: 2-Phenylfuro[3,2-b]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Phenylfuro[3,2-b]pyridine(18068-82-1)
• EPA Substance Registry System: 2-Phenylfuro[3,2-b]pyridine(18068-82-1)

Safety Data

• Hazardous Substances Data: 18068-82-1(Hazardous Substances Data)

Usage

General Description

2-Phenylfuro[3,2-b]pyridine is a chemical compound with a unique molecular structure that consists of a furo[3,2-b]pyridine core with a phenyl group attached to it. It is a heterocyclic aromatic compound that is synthesized through various chemical reactions. 2-Phenylfuro[3,2-b]pyridine has potential applications in materials science and drug discovery, particularly in the development of novel pharmaceuticals. Its unique structure and aromatic properties make it an interesting target for research and study in the field of organic chemistry. Additionally, its potential biological activities and pharmacological properties make it a promising candidate for further exploration in the development of new therapeutic agents.

Upstream product

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Relevant articles and documents

Copper- And ligand-free heteroannulation of o-halohydroxypyridine with terminal alkynes using Pd/C catalyst: One-pot synthesis of 2-substituted furopyridines and their functionalization

Three types of isomeric 2-substituted furo[3,2-b]pyridine, furo[2,3-b]pyridine and furo[3,2-c]pyridine were prepared using Pd/C-catalyzed heteroannulation of o-halopyridinols and terminal alkynes under copperand ligand-free conditions. We also demonstrated that double functionalization yielding 2,3-disubstituted furopyridines could be achieved through heteroannulation followed by bromination and Suzuki/Heck reactions. In addition, the use of recoverable Pd/C in the absence of a cocatalyst and ligand can aid in the development of greener chemical processes.

Facile synthesis of 2-substituted benzo[: B] furans and indoles by copper-catalyzed intramolecular cyclization of 2-alkynyl phenols and tosylanilines

A catalytic amount of CuCl and Cs2CO3 was employed to synthesize a variety of 2-substituted benzo[b]furans and indoles by an intramolecular cyclization of 2-alkynyl phenols and tosylanilines. This protocol features mild conditions, h

Synthesis of benzofurans from terminal alkynes and iodophenols catalyzed by recyclable palladium nanoparticles supported on N,O-dual doped hierarchical porous carbon under copper- and ligand-free conditions

We herein report that a stable and recyclable heterogeneous catalyst, consisting of Pd nanoparticles supported on N,O-dual doped hierarchical porous carbon derived from naturally available and renewable biomass-bamboo shoots, which allows for highly efficient one-pot tandem reaction of o-iodophenols with terminal alkynes to synthesize biologically active 2-benzofuran derivatives under copper- and ligand-free conditions. The catalyst performed superior catalytic performance compared with the analogous Pd/C and supported on other metal oxides under otherwise identical conditions. A broad set of aryl and alkyl terminal alkynes can be effectively coupled /cyclized with various o-iodophenols to afford their corresponding 2-benzofurans in good to high yields with good tolerance of multiple functional groups. Moreover, the catalyst showed good stability and could be reused several times without significant loss of activity.