1807-14-3

Basic information

• Product Name: 11-Deoxy Prednisolone
• Synonyms: 11-Deoxy Prednisolone;1,4-Reichstein S;17,21-Dihydroxypregna-1,4-diene-3,20-dione;17α,21-Dihydroxypregna-1,4- diene-3,20-dione;Δ'-Dehydrocortexolone;Prednisolone EP Impurity J
• CAS NO: 1807-14-3
• Molecular Formula: C21H28O4
• Molecular Weight: 344.44462
• Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
• Mol File: 1807-14-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator
• Solubility: Chloroform (Slightly, Heated, Sonicated), DMSO (Slightly, Sonicated), Ethanol (S
• Stability: Hygroscopic
• CAS DataBase Reference: 11-Deoxy Prednisolone(CAS DataBase Reference)
• NIST Chemistry Reference: 11-Deoxy Prednisolone(1807-14-3)
• EPA Substance Registry System: 11-Deoxy Prednisolone(1807-14-3)

Safety Data

• Hazardous Substances Data: 1807-14-3(Hazardous Substances Data)

Usage

Description

11-Deoxy Prednisolone, also known as Prednisolone EP Impurity J, is a derivative of Prednisolone (P703740). It is a corticosteroid, which is a type of steroid hormone that is naturally produced in the adrenal cortex. These hormones have various anti-inflammatory and immunosuppressive properties, making them useful in the treatment of a wide range of conditions.

Uses

Used in Pharmaceutical Industry:
11-Deoxy Prednisolone is used as a corticosteroid for its anti-inflammatory and immunosuppressive effects. It is particularly useful in the treatment of various conditions such as rheumatoid arthritis, lupus, asthma, and other autoimmune diseases. The application of 11-Deoxy Prednisolone in the pharmaceutical industry is due to its ability to modulate the immune system and reduce inflammation, providing relief from symptoms and managing the progression of the disease.
Used in Research and Development:
11-Deoxy Prednisolone is also used as a research compound in the development of new drugs and therapies. Its role as a corticosteroid derivative makes it a valuable tool for studying the mechanisms of action and potential applications of corticosteroids in various medical conditions. This application is important for advancing our understanding of corticosteroid function and for developing more effective treatments for a range of diseases.

Upstream product

• 152-58-9 Cortexolone 
• 974-23-2 3β-hydroxy-16α,17α-epoxypregn-5-en-20-one 
• 95871-37-7 17,21-diacetoxy-2α,4α-dibromo-5α-pregnane-3,20-dione 
• 96671-22-6 17,21-diacetoxy-3β-formyloxy-pregn-5-en-20-one 
• 115647-82-0 17,21-diacetoxy-3β-hydroxy-pregn-5-en-20-one 
• 96580-42-6 17,21-diacetoxy-5α-pregnane-3,20-dione 
• 20867-12-3 21-acetoxy-3β-formyloxy-17-hydroxy-pregn-5-en-20-one 
• 102958-34-9 5,6ξ,21-tribromo-3β-formyloxy-17-hydroxy-5ξ-pregnan-20-one 
• 171012-44-5 3β-formyloxy-17-hydroxy-21-iodo-pregn-5-en-20-one 
• 14072-39-0 16β-bromo-3β,17α-dihydroxypregn-5-ene-20-one 
• 20867-15-6 3β-formyloxy-17-hydroxy-pregn-5-en-20-one 
• 387-79-1 17-Hydroxypregnenolone 
• 640-87-9 cortexolone 21-acetate 
• 71842-04-1 17α,21-dihydroxypregna-1,4-diene-3,20-dione 17,21-diacetate 

Downstream Products

• 600-90-8 11α,17α,21-trihydroxypregna-1,4-diene-3,20-dione 
• 1249-67-8 17α,21-dihydroxypregna-1,4-diene-3,20-dione 21-acetate 

Relevant articles and documents

Process and intermediates for the preparation of 17 alphahydroxyprogesterones and corticoids from an enol steroid

This invention discloses an improved process for the production of corticoids from 17α-hydroxy steroids utilizing peroxymonosulfate.