1807530-07-9

Basic information

• Product Name: Azido-PEG3-PFP ester
• Synonyms: Azido-PEG3-PFP ester;N3-PEG3-PFP
• CAS NO: 1807530-07-9
• Molecular Formula: C15H16F5N3O5
• Molecular Weight: 413.296656
• Mol File: 1807530-07-9.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Solubility: Soluble in DMSO, DCM, DMF
• CAS DataBase Reference: Azido-PEG3-PFP ester(CAS DataBase Reference)
• NIST Chemistry Reference: Azido-PEG3-PFP ester(1807530-07-9)
• EPA Substance Registry System: Azido-PEG3-PFP ester(1807530-07-9)

Safety Data

• Hazardous Substances Data: 1807530-07-9(Hazardous Substances Data)

Usage

Description

Azido-PEG3-PFP ester is a PEG reagent consisting of an azide and PFP ester moieties. The azide is reactive with copper-catalyzed Click Chemistry reactions with propargyl, copper-free click chemistry with DBCO and BCN. The PFP ester is amine-reactive and is less susceptible toward hydrolysis compared to NHS ester.
Used in Bioconjugation:
Azido-PEG3-PFP ester is used as a bioconjugation agent for the attachment of biomolecules to various surfaces or nanoparticles. Its amine-reactive PFP ester allows for stable and specific coupling, while the azide group enables copper-catalyzed Click Chemistry reactions with propargyl, copper-free click chemistry with DBCO and BCN, providing versatile options for bioconjugation.
Used in Drug Delivery Systems:
Azido-PEG3-PFP ester is used as a component in drug delivery systems for the modification of nanoparticles or other drug carriers. Its amine-reactive PFP ester allows for the attachment of therapeutic agents or targeting ligands, while the azide group can be used for further functionalization or bioconjugation, enhancing the performance and targeting capabilities of drug delivery systems.
Used in Diagnostics and Imaging:
Azido-PEG3-PFP ester is used as a labeling agent for the modification of imaging agents or probes. Its amine-reactive PFP ester allows for the attachment to biomolecules or nanoparticles for specific targeting, while the azide group can be used for the incorporation of imaging moieties, such as fluorescent dyes or radioactive isotopes, enabling the development of novel diagnostic and imaging tools.
Used in Material Science:
Azido-PEG3-PFP ester is used as a functionalizing agent for the modification of various materials, such as polymers, surfaces, or nanoparticles. Its amine-reactive PFP ester allows for the attachment of PEG chains, improving the biocompatibility, stability, and stealth properties of the materials, while the azide group can be used for further functionalization or crosslinking, enabling the development of advanced materials with tailored properties for various applications.