180904-28-3

Basic information

• Product Name: (Z)-2-(2-Chloro-benzoyl)-3-(2,4-dichloro-phenylamino)-3-methylsulfanyl-acrylonitrile
• Synonyms: (Z)-2-(2-Chloro-benzoyl)-3-(2,4-dichloro-phenylamino)-3-methylsulfanyl-acrylonitrile
• CAS NO: 180904-28-3
• Molecular Weight: 397.712
• Mol File: 180904-28-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-2-(2-Chloro-benzoyl)-3-(2,4-dichloro-phenylamino)-3-methylsulfanyl-acrylonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-2-(2-Chloro-benzoyl)-3-(2,4-dichloro-phenylamino)-3-methylsulfanyl-acrylonitrile(180904-28-3)
• EPA Substance Registry System: (Z)-2-(2-Chloro-benzoyl)-3-(2,4-dichloro-phenylamino)-3-methylsulfanyl-acrylonitrile(180904-28-3)

Safety Data

• Hazardous Substances Data: 180904-28-3(Hazardous Substances Data)

Upstream product

• 554-00-7 2,4-Dichloroaniline 
• 175137-51-6 α-[bis(methylthio)methylene]-2-chloro-β-oxobenzenepropanenitrile 

Downstream Products

• 180904-37-4 1-(2,4-Dichloro-phenyl)-2-methylsulfanyl-4-oxo-1,4-dihydro-quinoline-3-carbonitrile 

Relevant articles and documents

Synthesis and activity of some quinolone derivatives against Plasmodium falciparum in vitro

Quinolones 7a-i and 8a-i were synthesized and tested in vitro as antimalarial against Plasmodium falciparum in chloroquine resistant strain. The above compounds were inactive at concentrations of 1.0 x 10-4 M except the quinolone 3-amino-9-(2,4-dichlorophenyl)-1H-pyrazolo[3,4-b]-4-quinolone 7h which showed IC50 of 5.06 μM given the most interesting results.