18092-17-6 Usage
Description
(2-hydroxy-5-oxo-1-phenyl-4,5-dihydro-1H-pyrrol-3-yl)(triphenyl)phosphonium, also known as Cyclic triphosphonium salt, is an organic compound that belongs to the phosphonium compound family. It consists of a phosphonium cation attached to a pyrrole moiety and is characterized by its aromatic phenyl and triphenylphosphine groups, as well as its 2-hydroxy-5-oxo-1-phenyl-4,5-dihydro-1H-pyrrol-3-yl functional group. (2-hydroxy-5-oxo-1-phenyl-4,5-dihydro-1H-pyrrol-3-yl)(triphenyl)phosphonium is commonly used in organic synthesis and as a catalyst in various chemical reactions. It has also been studied for its potential applications in medicinal chemistry, particularly in the development of novel drugs and pharmaceuticals, and exhibits interesting properties that make it a valuable tool in organometallic chemistry and materials science.
Uses
Used in Organic Synthesis:
(2-hydroxy-5-oxo-1-phenyl-4,5-dihydro-1H-pyrrol-3-yl)(triphenyl)phosphonium is used as a catalyst in organic synthesis for its ability to facilitate various chemical reactions, improving the efficiency and selectivity of the processes.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (2-hydroxy-5-oxo-1-phenyl-4,5-dihydro-1H-pyrrol-3-yl)(triphenyl)phosphonium is used as a key intermediate in the development of novel drugs and pharmaceuticals, owing to its unique structure and functional group.
Used in Organometallic Chemistry:
(2-hydroxy-5-oxo-1-phenyl-4,5-dihydro-1H-pyrrol-3-yl)(triphenyl)phosphonium is used as a valuable tool in organometallic chemistry due to its interesting properties, which make it suitable for various applications in this field.
Used in Materials Science:
In materials science, (2-hydroxy-5-oxo-1-phenyl-4,5-dihydro-1H-pyrrol-3-yl)(triphenyl)phosphonium is utilized for its potential to contribute to the development of new materials with unique properties and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 18092-17-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,0,9 and 2 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 18092-17:
(7*1)+(6*8)+(5*0)+(4*9)+(3*2)+(2*1)+(1*7)=106
106 % 10 = 6
So 18092-17-6 is a valid CAS Registry Number.
18092-17-6Relevant articles and documents
Synthesis and biological evaluation of thiazole derivatives as GPR119 agonists
Kim, Hyojin,Cho, Suk Joon,Yoo, Minjin,Kang, Seung Kyu,Kim, Kwang Rok,Lee, Hwan Hee,Song, Jin Sook,Rhee, Sang Dal,Jung, Won Hoon,Ahn, Jin Hee,Jung, Jae-Kyung,Jung, Kwan-Young
supporting information, p. 5213 - 5220 (2017/11/21)
A series of 4-(phenoxymethyl)thiazole derivatives was synthesized and evaluated for their GPR119 agonistic effect. Several 4-(phenoxymethyl)thiazoles with pyrrolidine-2,5-dione moieties showed potent GPR119 agonistic activities. Among them, compound 27 and 32d showed good in vitro activity with an EC50 value of 49 nM and 18 nM, respectively with improved human and rat liver microsomal stability compare with MBX-2982. Compound 27 & 32d did not exhibit significant CYP inhibition, hERG binding, and cytotoxicity. Moreover, these compounds lowered the glucose excursion in mice in an oral glucose-tolerance test.
Iridium-catalyzed asymmetric hydrogenation of α-alkylidene succinimides
Liu, Yuanyuan,Zhang, Wanbin
supporting information, p. 2203 - 2206 (2013/03/28)
Not to be out PhOXed! The title reaction provides a new approach to chiral succinimide derivatives with excellent yields and ee values by using a low catalyst loading (0.05 mol %) and mild reaction conditions. Chiral 3-benzyl pyrrolidines and 1-hydroxypyrrolidine-2,5-diones, important structural motifs in natural products and pharmaceuticals, could be readily prepared. BARF -=tetrakis[3,5-bis(trifluoromethyl)phenyl]borate. Copyright