181026-00-6

Basic information

• Product Name: 6-((2S,3R,4S,5R,6R)-4,5-Diacetoxy-6-acetoxymethyl-3-benzyloxy-tetrahydro-pyran-2-yloxy)-hexanoic acid methyl ester
• Synonyms: 6-((2S,3R,4S,5R,6R)-4,5-Diacetoxy-6-acetoxymethyl-3-benzyloxy-tetrahydro-pyran-2-yloxy)-hexanoic acid methyl ester
• CAS NO: 181026-00-6
• Molecular Weight: 524.565
• Mol File: 181026-00-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-((2S,3R,4S,5R,6R)-4,5-Diacetoxy-6-acetoxymethyl-3-benzyloxy-tetrahydro-pyran-2-yloxy)-hexanoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 6-((2S,3R,4S,5R,6R)-4,5-Diacetoxy-6-acetoxymethyl-3-benzyloxy-tetrahydro-pyran-2-yloxy)-hexanoic acid methyl ester(181026-00-6)
• EPA Substance Registry System: 6-((2S,3R,4S,5R,6R)-4,5-Diacetoxy-6-acetoxymethyl-3-benzyloxy-tetrahydro-pyran-2-yloxy)-hexanoic acid methyl ester(181026-00-6)

Safety Data

• Hazardous Substances Data: 181026-00-6(Hazardous Substances Data)

Upstream product

• 4547-43-7 methyl 6-hydroxycaproate 
• 173398-22-6 3,4,6-tri-O-acetyl-2-O-benzyl-β-D-glucopyranosyl bromide 
• 173314-28-8 phenyl 3,4,6-tri-O-acetyl-2-O-benzyl-1-thio-α-D-glucopyranoside 

Downstream Products

• 181026-02-8 6-[(2S,3R,4S,5R,6R)-4,5-Diacetoxy-6-acetoxymethyl-3-((3aR,4R,6R,7R,7aS)-4-acetoxymethyl-7-benzyloxy-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-6-yloxy)-tetrahydro-pyran-2-yloxy]-hexanoic acid methyl ester 
• 189144-74-9 C₅₆H₇₄O₂₅ 
• 189144-71-6 C₅₁H₇₀O₂₆ 
• 189144-72-7 C₄₈H₆₆O₂₆ 
• 189144-69-2 6-[(2S,3R,4S,5R,6R)-4,5-Diacetoxy-6-acetoxymethyl-3-((2R,3R,4S,5R,6R)-4,5-diacetoxy-6-acetoxymethyl-3-benzyloxy-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-2-yloxy]-hexanoic acid methyl ester 
• 189144-79-4 5-(methoxycarbonyl)pentyl O-(3,4,6-tri-O-acetyl-2-O-benzyl-α-D-glucopyranosyl)-(1->2)-O-(3,4,6-tri-O-acetyl-α-D-glucopyranosyl)-(1->2)-O-(3,4,6-tri-O-acetyl-α-D-glucopyranosyl)-(1->2)-3,4,6-tri-O-acetyl-α-D-glucopyranoside 

Relevant articles and documents

Synthesis of kojidextrins and their protein conjugates. Incidence of steric mismatch in oligosaccharide synthesis

Kojidextrins are biologically important oligosaccharides that are involved in many physiological processes including protein glycosylation and bacterial growth. As part of our project to explore the role kojidextrins may play in bacterial pathogenesis, here we report synthetic routes to kojibiose (54), -triose (58), -tetraose (64), and -pentaose (69) equipped with α-linked (hydrazinocarbonyl)pentyl aglycon, using linear and convergent strategies. In the search for a rapid convergent strategy for the construction of extended kojidextrins, four kojibiose donors (1-4) were synthesized that contain acyl- and ether-type protecting groups in various ratios. These were tested to probe the influence of diverse protecting group assemblies on their glycosyl donor ability. Attempted condensation of these donors with kojitriose and -tetraose acceptors failed to give the desired products apparently because of steric mismatch between the donor and the acceptor moieties. A one-pot procedure was developed for the covalent attachment of the synthetic saccharides through their hydrazido group to human serum albumin (HSA) using Tietze's squarate method to give neoglycoproteins containing up to 28 saccharide units per HSA.