18123-20-1Relevant articles and documents
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Corsini,Billo
, p. 1241,1245 (1970)
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Synthesis and Solvolysis of Acridine 1,2- and 3,4-Oxides: Crystal Structure of Acridine 1,2-Oxide
Boyd, Derek R.,Davies, R. Jeremy H.,Hamilton, Lynne,McCullough, John J.,Malone, John F.,et al.
, p. 984 - 990 (1994)
Acridine 1,2- and 3,4-oxides were synthesized from 3,4- and 1,2-dihydroacridine, respectively, via intermediate bromohydrin acetates.Crystals of acridine 1,2-oxide were sufficiently stable to allow the first determination of X-ray crystallographic structu
NEUROLOGICALLY-ACTIVE COMPOUNDS
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Page 73, (2010/02/06)
The present invention relates to neurologically-active compounds, being heterocyclic compounds having two fused 6-membered rings with a nitrogen atom at position 1 and a hydroxy or mercapto group at position 8 with at least one ring being aromatic. Also disclosed are processes for the preparation of these compounds and their use as pharmaceutical or veterinary agents, in particular for the treatment of neurological conditions, more specifically neurodegenerative conditions such as Alzheimer's disease.