181284-95-7 Usage
Chemical class
Benzimidazole derivatives
Functional groups
Ester, Amine
Structure
1H-Benzimidazole-5-carboxylic acid with a 6-amino group and a methyl ester group
Solubility
Improved solubility due to the methyl ester group
Bioavailability
Enhanced bioavailability due to the methyl ester group
Applications
Used in the synthesis of pharmaceuticals and agricultural chemicals
Biological activities
Potential anti-tumor and anti-inflammatory properties
Interest
Significant interest in research and development for new drugs and agricultural products
Therapeutic applications
Potential use in the development of therapeutic agents
Agricultural applications
Potential use in the development of agricultural products with improved properties
Check Digit Verification of cas no
The CAS Registry Mumber 181284-95-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,1,2,8 and 4 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 181284-95:
(8*1)+(7*8)+(6*1)+(5*2)+(4*8)+(3*4)+(2*9)+(1*5)=147
147 % 10 = 7
So 181284-95-7 is a valid CAS Registry Number.
181284-95-7Relevant articles and documents
Synthesis, biological evaluation, and crystallographic studies of extended guanine-based (lin-benzoguanine) inhibitors for tRNA-guanine transglycosylase (TGT)
Meyer, Emmanuel A.,Donati, Nicola,Guillot, Marine,Schweizer, W. Bernd,Diederich, Francois,Stengl, Bernhard,Brenk, Ruth,Reuter, Klaus,Klebe, Gerhard
, p. 573 - 581 (2007/10/03)
This paper describes the rational design, synthesis, and biological evaluation of a new generation of inhibitors of the bacterial enzyme tRNA-guanine transglycosylase (TGT), which has been identified as a new target in the fight against bacillary dysenter