18133-14-7Relevant articles and documents
Bcl-2 INHIBITORS
-
, (2019/11/19)
Disclosed herein is a compound of Formula (I) for inhibiting Bcl-2 and treating disease associated with undesirable bcl-2 activity (Bcl-2 related diseases), a method of using the compounds disclosed herein for treating dysregulated apoptotic diseases including cancers and treating autoimmune disease, and a pharmaceutical composition comprising the same.
On the phenyliodine(III)-bis(trifluoroacetate)-mediated olefin amidohydroxylation reaction
Tellitu, Imanol,Urrejola, Andrea,Serna, Sonia,Moreno, Isabel,Herrero, M. Teresa,Dominguez, Esther,SanMartin, Raul,Correa, Arkaitz
, p. 437 - 444 (2008/02/03)
When appropriately substituted amides are treated with PIFA in a non-nudeophilic solvent like trifluoroethanol, a stable N-acylnitrenium ion is generated. If under such conditions a C=C double bond is present in the molecule, an intramolecular cyclization