181363-91-7

Basic information

• Product Name: N¹-benzyl-N¹⁰-[5,6-dicarbomethoxy-3-(1,2,4-triazinyl)]-(L)-tryptophan methyl ester
• Synonyms: N¹-benzyl-N¹⁰-[5,6-dicarbomethoxy-3-(1,2,4-triazinyl)]-(L)-tryptophan methyl ester
• CAS NO: 181363-91-7
• Molecular Weight: 503.514
• Mol File: 181363-91-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N¹-benzyl-N¹⁰-[5,6-dicarbomethoxy-3-(1,2,4-triazinyl)]-(L)-tryptophan methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N¹-benzyl-N¹⁰-[5,6-dicarbomethoxy-3-(1,2,4-triazinyl)]-(L)-tryptophan methyl ester(181363-91-7)
• EPA Substance Registry System: N¹-benzyl-N¹⁰-[5,6-dicarbomethoxy-3-(1,2,4-triazinyl)]-(L)-tryptophan methyl ester(181363-91-7)

Safety Data

• Hazardous Substances Data: 181363-91-7(Hazardous Substances Data)

Upstream product

• 4299-70-1 L-tryptophan methyl ester 
• 73-22-3 L-Tryptophan 
• 219497-33-3 3-(1-benzyl-1H-indol-3-yl)-2-tert-butoxycarbonylamino-propionic acid methyl ester 
• 141215-69-2 methyl (2S)-2-{[(tert-butoxy)carbonyl]amino}-3-(1H-indol-3-yl)propanoate 
• 108005-26-1 Dimethyl 3-(methylthio)-1,2,4-triazine-5,6-dicarboxylate 
• 129784-64-1 N¹-benzyl-(L)-tryptophan methyl ester 

Downstream Products

• 1203571-97-4 C₂₈H₂₄F₃N₃O₇ 

Relevant articles and documents

New small molecule inhibitors of hepatitis C virus

New small molecule inhibitors of HCV were discovered by screening a small library of indoline alkaloid-type compounds. An automated assay format was employed which allowed identification of dimerization inhibitors of core, the capsid protein of the virus. These compounds were subsequently shown to block production of infectious virus in hepatoma cells.

Inverse electron demand Diels-Alder reactions of indole V. Reactions of 3-substituted indoles with heteroaromatic azadienes

The inverse electron demand Diels-Alder reactions of 3-substituted indoles with 1,2,4-triazines and 1,2,4,5-tetrazines proceeded in excellent yields both inter- and intramolecularly. The cycloaddition of tryptophan with a tethered 1,2,4-triazine produced a diastereomerically pure cycloadduct.