181419-96-5

Basic information

• Product Name: 1-O-allyl-13-O-[(2R,3S)-3-(tert-butoxycarbonylamino)-3-phenyl-2-(triethylsilyloxy)propionyl]-10-deacetyl-7-O-triethylsilylbaccatin III
• Synonyms: 1-O-allyl-13-O-[(2R,3S)-3-(tert-butoxycarbonylamino)-3-phenyl-2-(triethylsilyloxy)propionyl]-10-deacetyl-7-O-triethylsilylbaccatin III
• CAS NO: 181419-96-5
• Molecular Weight: 1076.48
• Mol File: 181419-96-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-O-allyl-13-O-[(2R,3S)-3-(tert-butoxycarbonylamino)-3-phenyl-2-(triethylsilyloxy)propionyl]-10-deacetyl-7-O-triethylsilylbaccatin III(CAS DataBase Reference)
• NIST Chemistry Reference: 1-O-allyl-13-O-[(2R,3S)-3-(tert-butoxycarbonylamino)-3-phenyl-2-(triethylsilyloxy)propionyl]-10-deacetyl-7-O-triethylsilylbaccatin III(181419-96-5)
• EPA Substance Registry System: 1-O-allyl-13-O-[(2R,3S)-3-(tert-butoxycarbonylamino)-3-phenyl-2-(triethylsilyloxy)propionyl]-10-deacetyl-7-O-triethylsilylbaccatin III(181419-96-5)

Safety Data

• Hazardous Substances Data: 181419-96-5(Hazardous Substances Data)

Upstream product

• 115437-18-8 7-triethylsilyl-10-deacetylbaccatin III 
• 149198-47-0 tert-butyl (3R,4S)-2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate 
• 181419-93-2 10-O-allyl-10-deacetyl-7-O-triethylsilylbaccatin III 

Downstream Products

• 181421-40-9 C₆₁H₉₂N₂O₁₄SSi₂ 
• 181420-07-5 C₆₁H₉₂N₂O₁₅Si₂ 
• 181420-02-0 13-O-[(2R,3S)-3-(tert-butoxycarbonylamino)-3-phenyl-2-(triethylsilyloxy)propionyl]-10-deacetyl-10-O-formylmethyl-7-O-triethylsilylbaccatin 

Relevant articles and documents

Synthesis and evaluation of water-soluble non-prodrug analogs of docetaxel bearing sec-aminoethyl group at the C-10 position

To develop non-prodrugs of taxoids with satisfactory stability in vivo, high water-solubility, and potent antitumor activity, we prepared several 10- O-sec-aminoethyl docetaxel analogs (3) and evaluated their cytotoxicity against mouse leukemia and human