181581-97-5

Basic information

• Product Name: 2-((2S,3S,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-3,5-dimethoxy-pyrazine
• CAS NO: 181581-97-5
• Molecular Weight: 542.632
• Mol File: 181581-97-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-((2S,3S,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-3,5-dimethoxy-pyrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((2S,3S,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-3,5-dimethoxy-pyrazine(181581-97-5)
• EPA Substance Registry System: 2-((2S,3S,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-3,5-dimethoxy-pyrazine(181581-97-5)

Safety Data

• Hazardous Substances Data: 181581-97-5(Hazardous Substances Data)

Upstream product

• 14233-64-8 (3R,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-dihydro-furan-2-one 
• 4774-15-6 2,6-dimethoxypyrazine 
• 181582-02-5 (3R,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-2-(3,5-dimethoxy-pyrazin-2-yl)-tetrahydro-furan-2-ol 

Relevant articles and documents

Synthesis of pyrazine C-ribosides via direct metalation

A direct metalation method has been developed for the synthesis of novel pyrazine C-nucleosides. The regiochemistry was controlled by selecting different substituents on the pyrazine ring and excellent stereoselectivity was achieved via a hydride delivery strategy. The scope and limitations of this method were studied. The uniquely designed 4b is a versatile synthon for the preparation of other pyrazine C-nucleosides.