181582-00-3

Basic information

• Product Name: (3R,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-2-(5-chloro-3-methoxy-pyrazin-2-yl)-tetrahydro-furan-2-ol
• CAS NO: 181582-00-3
• Molecular Weight: 563.05
• Mol File: 181582-00-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3R,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-2-(5-chloro-3-methoxy-pyrazin-2-yl)-tetrahydro-furan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-2-(5-chloro-3-methoxy-pyrazin-2-yl)-tetrahydro-furan-2-ol(181582-00-3)
• EPA Substance Registry System: (3R,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-2-(5-chloro-3-methoxy-pyrazin-2-yl)-tetrahydro-furan-2-ol(181582-00-3)

Safety Data

• Hazardous Substances Data: 181582-00-3(Hazardous Substances Data)

Upstream product

• 14233-64-8 (3R,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-dihydro-furan-2-one 
• 33332-30-8 2-chloro-6-methoxypyrazine 

Downstream Products

• 181581-95-3 2-((2S,3S,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-5-chloro-3-methoxy-pyrazine 

Relevant articles and documents

Synthesis of pyrazine C-ribosides via direct metalation

A direct metalation method has been developed for the synthesis of novel pyrazine C-nucleosides. The regiochemistry was controlled by selecting different substituents on the pyrazine ring and excellent stereoselectivity was achieved via a hydride delivery strategy. The scope and limitations of this method were studied. The uniquely designed 4b is a versatile synthon for the preparation of other pyrazine C-nucleosides.