181657-57-8 Usage
Description
(1S,2S)-(+)-2-Benzyloxycyclopentylamine is an important organic intermediate with significant applications across various industries due to its unique chemical properties and reactivity. It is particularly valuable in stereoselective organic synthesis, where it can be utilized as a resolving agent, building block, or chiral auxiliary, contributing to the development of enantiomerically pure compounds.
Uses
Used in Agrochemical Industry:
(1S,2S)-(+)-2-Benzyloxycyclopentylamine is used as a key intermediate for the synthesis of various agrochemicals, such as pesticides and herbicides. Its role in this industry is crucial for the development of effective and selective compounds that can target specific pests or weeds without causing harm to the environment or non-target organisms.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (1S,2S)-(+)-2-Benzyloxycyclopentylamine is employed as a building block or chiral auxiliary in the synthesis of enantiomerically pure drugs. The importance of chirality in drug development cannot be overstated, as the efficacy and safety of a drug can be highly dependent on its stereochemistry. This organic intermediate helps in the creation of drugs with improved pharmacological properties and reduced side effects.
Used in Dyestuff Industry:
(1S,2S)-(+)-2-Benzyloxycyclopentylamine is also used in the dyestuff industry for the production of chiral dyes and pigments. These chiral compounds can exhibit unique color properties and are valuable in various applications, such as in the textile industry for the creation of vibrant and long-lasting colors, as well as in the development of advanced materials with specific optical properties.
Check Digit Verification of cas no
The CAS Registry Mumber 181657-57-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,1,6,5 and 7 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 181657-57:
(8*1)+(7*8)+(6*1)+(5*6)+(4*5)+(3*7)+(2*5)+(1*7)=158
158 % 10 = 8
So 181657-57-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H17NO/c13-11-7-4-8-12(11)14-9-10-5-2-1-3-6-10/h1-3,5-6,11-12H,4,7-9,13H2/t11-,12-/m0/s1
181657-57-8Relevant articles and documents
Hybrid Organo- and Biocatalytic Process for the Asymmetric Transformation of Alcohols into Amines in Aqueous Medium
Liardo, Elisa,Ríos-Lombardía, Nicolás,Morís, Francisco,Rebolledo, Francisca,González-Sabín, Javier
, p. 4768 - 4774 (2017/07/24)
A hybrid organo- and biocatalytic system for the asymmetric conversion of racemic alcohols into amines was developed. Combining an organocatalyst, AZADO, an oxidant, NaOCl, and an enzyme, ω-transaminase, we implemented a one-pot oxidation-transamination sequential process in aqueous medium. The method showed broad substrate scope and was successfully applied to conventional secondary alcohols and sterically hindered β-substituted cycloalkanols, where a highly stereoselective dynamic asymmetric bioamination enabled us to set up both contiguous stereocenters with very high enantio- and diastereomeric ratio (>90% yield, >99% ee, and up to 49:1 dr).
COMBINATION OF BENZOTHIAZOL-2-ONE BETA2 ADRENOCEPTOR AGONISTS AND CORTICOSTEROIDS FOR THE TREATMENT OF RESPIRATORY DISEASES
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Page/Page column 30, (2010/02/13)
A medicament comprising, separately or together, (A) a compound of Formula (I) in free or salt or solvate form, wherein X has the meaning as indicated in the specification; and (B) a corticosteroid, for simultaneous, sequential or separate administration in the treatment of an inflammatory obstructive airways disease, the molar ratio of (A) to (B) being from 100:1 to 1:300.
