1818-66-2 Usage
General Description
1,3,7-trimethyl-8-propoxy-3,7-dihydro-1H-purine-2,6-dione, also known as caffeine, is a naturally occurring chemical compound that acts as a central nervous system stimulant. It is found in various plant sources, including coffee beans, tea leaves, and cacao pods. Caffeine is commonly consumed as a psychoactive drug and a mild diuretic, and it is an active ingredient in many popular beverages like coffee, tea, and energy drinks. Its stimulant effects are attributed to its ability to block adenosine receptors in the brain, leading to increased alertness and energy levels. Caffeine also has known effects on metabolism, improving athletic performance, and enhancing cognitive function. However, excessive consumption of caffeine can lead to negative side effects, such as insomnia, anxiety, and heart palpitations.
Check Digit Verification of cas no
The CAS Registry Mumber 1818-66-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,1 and 8 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1818-66:
(6*1)+(5*8)+(4*1)+(3*8)+(2*6)+(1*6)=92
92 % 10 = 2
So 1818-66-2 is a valid CAS Registry Number.
1818-66-2Relevant articles and documents
Electrochemical C?H Functionalization of (Hetero)Arenes—Optimized by DoE
D?rr, Maurice,R?ckl, Johannes L.,Rein, Jonas,Schollmeyer, Dieter,Waldvogel, Siegfried R.
supporting information, p. 10195 - 10198 (2020/07/04)
A novel approach towards the activation of different arenes and purines including caffeine and theophylline is presented. The simple, safe and scalable electrochemical synthesis of 1,1,1,3,3,3-hexafluoroisopropanol (HFIP) aryl ethers was conducted using an easy electrolysis setup with boron-doped diamond (BDD) electrodes. Good yields up to 59 percent were achieved. Triethylamine was used as a base as it forms a highly conductive media with HFIP, making additional supporting electrolytes superfluous. The synthesis was optimized using Design of Experiment (DoE) techniques giving a detailed insight to the significance of the reaction parameters. The mechanism was investigated by cyclic voltammetry (CV). Subsequent transition metal-catalyzed as well as metal-free functionalization led to interesting motifs in excellent yields up to 94 percent.
