18189-05-4

Basic information

• Product Name: hexyl anthranilate
• Synonyms: hexyl anthranilate;n-Hexyl o-aminobenzoate;2-Aminobenzoic acid hexyl ester;Anthanilic acid hexyl ester;hexyl 2-aminobenzoate
• CAS NO: 18189-05-4
• Molecular Formula: C₁₃H₁₉NO₂
• Molecular Weight: 221.29546
• EINECS: 242-075-4
• Mol File: 18189-05-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 328.6°C at 760 mmHg
• Flash Point: 178.4°C
• Appearance: /
• Density: 1.043g/cm³
• Vapor Pressure: 0.000188mmHg at 25°C
• Refractive Index: 1.528
• CAS DataBase Reference: hexyl anthranilate(CAS DataBase Reference)
• NIST Chemistry Reference: hexyl anthranilate(18189-05-4)
• EPA Substance Registry System: hexyl anthranilate(18189-05-4)

Safety Data

• Hazardous Substances Data: 18189-05-4(Hazardous Substances Data)

Usage

General Description

Hexyl anthranilate, also known as helional, is an organic compound commonly used in the fragrance industry. It is a clear, colorless liquid with a sweet, floral scent and is often used as a synthetic substitute for jasmine and orange blossom fragrances. Hexyl anthranilate is known for its long-lasting scent and is frequently used in cosmetic products, perfumes, and air fresheners. Additionally, it is commonly used in sunscreen and tanning lotions to impart a pleasant, tropical aroma. Furthermore, this chemical is considered safe for use in consumer products and has low toxicity, making it a popular choice for fragrance applications.

InChI:InChI=1/C13H19NO2/c1-2-3-4-7-10-16-13(15)11-8-5-6-9-12(11)14/h5-6,8-9H,2-4,7,10,14H2,1H3

Upstream product

• 117375-30-1 2-nitrobenzoic acid 1-hexyl ester 
• 552-16-9 ortho-nitrobenzoic acid 
• 111-27-3 hexan-1-ol 
• 118-92-3 anthranilic acid 

Downstream Products

• 67836-75-3 2-(3,4-Dimethoxy-benzoylamino)-benzoic acid hexyl ester 
• 180132-98-3 2-(2-nitro-4-methoxycarbonylbenzoylamino)benzoic acid 1-hexyl ester 
• 196311-84-9 2-(2-nitrobenzoylamino)benzoic acid 1-hexyl ester 
• 657412-92-5 2,5-Bis-hexyloxy-N-(2-hexyloxycarbonyl-phenyl)-terephthalamic acid benzyl ester 
• 180335-21-1 C₁₉H₂₃N₃O₂ 
• 180132-99-4 2-(2-amino-4-methoxycarbonylbenzoylamino)benzoic acid 1-hexyl ester 
• 180133-09-9 2-[2-(2-aminobenzoylamino)-4-methoxycarbonylbenzoylamino]benzoic acid 1-hexyl ester 
• 182301-30-0 2-[2-(2-nitrobenzoylamino)-4-methoxycarbonylbenzoylamino]benzoic acid 1-hexyl ester 
• 180133-11-3 2-{2-[2-(2-amino-4-methoxycarbonylbenzoylamino)benzoylamino]-4-methoxycarbonylbenzoylamino}benzoic acid 1-hexyl ester 
• 180133-10-2 2-{2-[2-(2-nitro-4-methoxycarbonylbenzoylamino)benzoylamino]-4-methoxycarbonylbenzoylamino}benzoic acid 1-hexyl ester 
• 180133-01-1 2-{2-[2-(2-hexanoylamino-4-hydroxycarbonylbenzoylamino)benzoylamino]-4-hydroxycarbonylbenzoylamino}benzoic acid 1-hexyl ester 
• 180133-00-0 2-{2-[2-(2-hexanoylamino-4-methoxycarbonylbenzoylamino)benzoylamino]-4-methoxycarbonylbenzoylamino}benzoic acid 1-hexyl ester 

Relevant articles and documents

Synthesis, antimicrobial evaluation, ot-QSAR and mt-QSAR studies of 2-amino benzoic acid derivatives

A series of 2-amino benzoic acid derivatives (1-28) were synthesized and evaluated for their in vitro antimicrobial activity against the panel of Gram positive, Gram negative bacterial and fungal strains. The results of antimicrobial studies indicated that, in general, the synthesized compounds were found to be bacteriostatic and fungistatic in action. QSAR studies performed by the development of one target and multi target models indicated that multi-target model was effective in describing the antimicrobial activity as well demonstrated the effect of structural parameters viz. LUMO, 3χv and W on antimicrobial activity of 2-amino benzoic acid derivatives. Springer Science+Business Media, LLC 2010.

Steric effects in acid-catalyzed decomposition and base-catalyzed cyclization of 1-(2-alkoxycarbonyl-phenyl)-3-phenyltriazenes

Eight derivatives of 1-(2-alkoxycarbonylphenyl)-3-phenyltriazene (R = methyl, ethyl, propyl, isopropyl, butyl, isobutyl, hexyl, and allyl) have been synthesized and their UV-VIS, IR, 1H and 13C NMR spectra measured. The NMR spectra have been interpreted in detail. The kinetics of acid-catalyzed decomposition and base-catalyzed cyclization of the title compounds have been measured in 52.1% w/w methanol at 25.0 °C. The unit reaction order has been verified and the cyclization product has been identified. The pH-profiles obtained have been used to calculate the catalytic rate constants kA (acid-catalyzed decomposition) and kB (base-catalyzed cyclization) of all the derivatives; the constants have been interpreted with regard to inductive and steric effects. The catalytic rate constant kA has been found to be independent of the substituents. The catalytic rate constant kB depends statistically significantly upon both inductive and steric effects, the sensitivity to the former being more significant. The experimental results and their interpretation confirm the base-catalyzed cyclization mechanism with formation of tetrahedral intermediate as the rate-limiting step.