182005-32-9Relevant articles and documents
Facile new method for preparation of optically active protected proline
Yamaguchi, Jun-Ichi,Ueki, Masaaki
, p. 621 - 622 (2007/10/03)
Treatment of L-N-protected 2-amino-5-bromopentanoic acid ester, which was prepared from protected L-glutamic acid, with sodium hydride in tetrahydrofuran (THF) proceeded to give the corresponding protected L-proline in high yield. On the other hand, the reaction of 2-aminobutyric acid derivative with sodium hydride gave the 1-aminocyclopropane-1-carboxylic acid derivative.