18212-62-9 Usage
Description
4-METHYL-1,2,3-THIADIAZOLE is a heterocyclic compound that features a thiadiazole ring with a methyl substituent. It is widely recognized for its versatile reactivity and potential medicinal properties, making it a valuable building block in organic synthesis and pharmaceutical research. Additionally, this chemical is utilized as a ligand in coordination chemistry, particularly for the formation of metal complexes. Its potential applications extend to the development of new drugs, agricultural chemicals, and materials science, with ongoing research into its antimicrobial, antifungal, and antioxidant properties.
Uses
Used in Pharmaceutical Research:
4-METHYL-1,2,3-THIADIAZOLE is used as a building block in the synthesis of new drugs due to its versatile reactivity and potential medicinal properties.
Used in Organic Synthesis:
4-METHYL-1,2,3-THIADIAZOLE is employed as a key component in the creation of various organic compounds, leveraging its unique structure and reactivity.
Used in Coordination Chemistry:
4-METHYL-1,2,3-THIADIAZOLE is used as a ligand in the formation of metal complexes, contributing to the development of coordination chemistry.
Used in Materials Science:
4-METHYL-1,2,3-THIADIAZOLE is utilized in the development of new materials, taking advantage of its chemical properties and potential applications in this field.
Used in Agricultural Chemicals:
4-METHYL-1,2,3-THIADIAZOLE is used in the development of agricultural chemicals, potentially enhancing crop protection and yield.
Used in Antimicrobial Applications:
4-METHYL-1,2,3-THIADIAZOLE is studied for its antimicrobial properties, which could lead to the development of new treatments and preventive measures against microbial infections.
Used in Antifungal Applications:
4-METHYL-1,2,3-THIADIAZOLE is investigated for its antifungal properties, with potential applications in combating fungal infections and diseases.
Used in Antioxidant Research:
4-METHYL-1,2,3-THIADIAZOLE is explored for its antioxidant properties, which may contribute to the development of new antioxidants for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 18212-62-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,2,1 and 2 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 18212-62:
(7*1)+(6*8)+(5*2)+(4*1)+(3*2)+(2*6)+(1*2)=89
89 % 10 = 9
So 18212-62-9 is a valid CAS Registry Number.
InChI:InChI=1/C3H4N2S/c1-3-2-6-5-4-3/h2H,1H3
18212-62-9Relevant articles and documents
Sterically controlled diastereoselectivity in thio-Staudinger cycloadditions of alkyl/alkenyl/aryl-substituted thioketenes
He, Wei,Zhuang, Junpeng,Yang, Zhanhui,Xu, Jiaxi
, p. 5541 - 5548 (2017)
The [2 + 2] cycloadditions of thioketenes and imines are named as thio-Staudinger cycloadditions. The diastereoselectivity in thio-Staudinger cycloaddtions of alkyl/alkenyl/aryl-substituted thioketenes is rationalized. The steric effects of the thioketenes play an extremely important role in deciding the diastereoselectivity (cis/trans selectivity) through controlling exo- and endo-attack and subsequent ring closure. The conclusion is further supported by our additional experimental and calculational results. The isomerization of the iminium moiety in zwitterionic intermediates generated from the thioketenes and linear imines also affects the diastereoselectivity. The electronic effect of imine substituents slightly impacts the diastereoselectivity, while epimerization of cis-β-thiolactams to trans-diastereomers is a significant factor in the thio-Staudinger cycloadditions of mono-substituted thioketenes under basic conditions.
Traceless solid-phase synthesis of 1,2,3-thiadiazole derivatives from resin-bound acylhydrazine
Liu, Zhanxiang,Mu, Yuanyuan,Lin, Jie,Chen, Yiya
experimental part, p. 4407 - 4414 (2009/04/11)
A novel synthesis of 1,2,3-thiadiazole derivatives using a traceless solid-phase approach is described, in which many kinds of 1,2,3-thiadiazole derivatives were efficiently obtained in good yields and high purities via traceless cyclization cleavage of resin-bound acylhydrazones with thionyl chloride. Copyright Taylor & Francis Group, LLC.
