182132-20-3

Basic information

• Product Name: Toluene-4-sulfonic acid 3-(2,5-dimethoxy-phenyl)-1-methyl-propyl ester
• CAS NO: 182132-20-3
• Molecular Weight: 364.463
• Mol File: 182132-20-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Toluene-4-sulfonic acid 3-(2,5-dimethoxy-phenyl)-1-methyl-propyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Toluene-4-sulfonic acid 3-(2,5-dimethoxy-phenyl)-1-methyl-propyl ester(182132-20-3)
• EPA Substance Registry System: Toluene-4-sulfonic acid 3-(2,5-dimethoxy-phenyl)-1-methyl-propyl ester(182132-20-3)

Safety Data

• Hazardous Substances Data: 182132-20-3(Hazardous Substances Data)

Upstream product

• 118709-30-1 trans-1-(2,5-dimethoxyphenyl)-2-buten-3-one 
• 93-02-7 2,5-dimethoxybenzaldehyde 
• 98-59-9 p-toluenesulfonyl chloride 
• 147249-35-2 (+/-)-1-(2,5-Dimethoxyphenyl)butan-3-ol 

Downstream Products

• 86341-38-0 crotyl-1,4-dimethoxybenzene 

Relevant articles and documents

High pressure nucleophilic fluoride-ion substitution reactions: Formation of fluoroalkylbenzenes

A series of 1-phenyl-2-tosyloxy- and 1-phenyl-3-tosyloxyalkanes was synthesized and then subjected to tetrabutylammonium fluoride in THF under 15 kbar (1.5 GPa), 8 kbar or 1 bar pressures. The resultant substitution and elimination reaction product distributions were analyzed. The application of pressure enhanced the progress of the fluoride-ion substitution reactions. The degree of selectivity of the one reaction over the other was found to be a function of tosylate substrate structure and the amount of pressure applied. The exclusive formation of fluoroalkanes from 1-phenyl-2-tosyloxyalkane substrates under 15 kbar pressure demonstrated the potential of the pressure method for prospective use in fluorine-18 radiolabelling applications.