182155-26-6Relevant articles and documents
Diastereoselective addition of grignard reagents to azetidine-23-dione: Synthesis of novel taxol analogues
Kant, Joydeep,Schwartz, Wendy S.,Fairchild, Craig,Gao, Qi,Huang, Stella,Long, Byron H.,Kadow, John F.,Langley, David R.,Farina, Vittorio,Vyas, Dolatrai
, p. 6495 - 6498 (2007/10/03)
Synthesis and cytotoxicity properties of novel C-2' analogues of paclitaxel are described. The analogues were synthesized using Holton's β-lactam approach to append the side chain on baccatin III. The key intermediate to the synthesis of novel analogues w