1822-94-2

Basic information

• Product Name: 5-(CHLOROMETHYL)-3-PHENYL-1,2,4-OXADIAZOLE
• Synonyms: AKOS BB-7023;5-(CHLOROMETHYL)-3-PHENYL-1,2,4-OXADIAZOLE;CHEMBRDG-BB 4017587;5-Chloromethyl-3-(4-fluoro-phenyl)-;5-(chloromethyl)-3-phenyl-1,2,4-oxadiazole(SALTDATA: FREE);1,2,4-Oxadiazole, 5-(chloromethyl)-3-phenyl-;3-Phenyl-5-chloromethyl-1,2,4-oxadiazole
• CAS NO: 1822-94-2
• Molecular Formula: C₉H₇ClN₂O
• Molecular Weight: 194.62
• Mol File: 1822-94-2.mol
• Article Data: 31

Chemical Properties

• Melting Point: 42 °C
• Boiling Point: 142 °C
• Flash Point: 145.5°C
• Appearance: /
• Density: 1.283
• Vapor Pressure: 0.00103mmHg at 25°C
• Refractive Index: 1.542
• Storage Temp.: 2-8°C
• PKA: -2?+-.0.32(Predicted)
• CAS DataBase Reference: 5-(CHLOROMETHYL)-3-PHENYL-1,2,4-OXADIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(CHLOROMETHYL)-3-PHENYL-1,2,4-OXADIAZOLE(1822-94-2)
• EPA Substance Registry System: 5-(CHLOROMETHYL)-3-PHENYL-1,2,4-OXADIAZOLE(1822-94-2)

Safety Data

• Hazard Codes: C,Xn
• Statements: 22
• Hazardous Substances Data: 1822-94-2(Hazardous Substances Data)

Usage

General Description

5-(Chloromethyl)-3-phenyl-1,2,4-oxadiazole is a chemical compound with the molecular formula C9H7ClN2O. It is a heterocyclic organic compound that contains an oxadiazole ring, as well as a phenyl group and a chloromethyl group. 5-(CHLOROMETHYL)-3-PHENYL-1,2,4-OXADIAZOLE has potential applications in the fields of pharmaceuticals and agrochemicals, as well as in material science. It has been studied for its biological activities, such as antibacterial and antifungal properties. Additionally, it has been investigated for its potential as a building block for the synthesis of other organic compounds with useful properties. Overall, 5-(chloromethyl)-3-phenyl-1,2,4-oxadiazole is a versatile chemical with a range of potential applications in various industries.

InChI:InChI=1/C9H6ClFN2O/c10-5-8-12-9(13-14-8)6-1-3-7(11)4-2-6/h1-4H,5H2

Upstream product

• 873-67-6 benzonitrile oxide 
• 107-14-2 chloroacetonitrile 
• 21251-95-6 N-chloroacetoxy-benzamidine 
• 79-04-9 chloroacetyl chloride 
• 613-92-3 N-hydroxybenzenecarboximidamide 
• 2549-51-1 vinyl chloroacetate 
• 21251-95-6 (Z)-N'-(2-chloroacetoxy)benzimidamide 
• 613-92-3 N-hydroxyl-benzamidine 
• 22118-09-8 2-bromoacetyl chloride 
• 613-92-3 N-hydroxybenzamidine 
• 100-47-0 benzonitrile 
• 613-92-3 (E)-N'-hydroxybenzimidamide 
• 1401223-69-5 C₉H₉ClN₂O₂ 

Downstream Products

• 91959-17-0 3-phenyl-5-pyrrolidin-1-ylmethyl-[1,2,4]oxadiazole 
• 92440-02-3 3-phenyl-5-(piperidin-1-ylmethyl)-1,2,4-oxadiazole 
• 91959-44-3 4-(3-phenyl-[1,2,4]oxadiazol-5-ylmethyl)-morpholine 
• 93760-73-7 5-[(4-methylpiperazin-1-yl)methyl]-3-phenyl-1,2,4-oxadiazole 
• 73217-38-6 1-(3-phenyl-[1,2,4]oxadiazol-5-ylmethyl)-pyridinium; chloride 
• 93475-45-7 isobutyl-(3-phenyl-[1,2,4]oxadiazol-5-ylmethyl)-amine 
• 5539-87-7 5-[trans-3-(4-nitro-phenyl)-oxiranyl]-3-phenyl-[1,2,4]oxadiazole 
• 5543-31-7 5-acetoxymethyl-3-phenyl-[1,2,4]oxadiazole 
• 4915-88-2 3-phenyl-5-((phenylthio)methyl)-1,2,4-oxadiazole 
• 91643-11-7 isopropyl-[(3-phenyl-[1,2,4]oxadiazol-5-yl)methyl]amine 
• 49772-99-8 2-methyl-2-(3-phenyl-[1,2,4]oxadiazol-5-ylmethylsulfanyl)-propionic acid ethyl ester 
• 7435-30-5 2,3-bis(3-phenyl-1,2,4-oxadiazol-5-yl)-2-((3-phenyl-1,2,4-oxadiazol-5-yl)methyl)propanenitrile 
• 4915-89-3 3-phenyl-5-(thiocyanatomethyl)-1,2,4-oxadiazole 
• 55983-96-5 5-Methylaminomethyl-3-phenyl-1.2.4-oxadiazol 

Relevant articles and documents

In vitro anti-TB properties, in silico target validation, molecular docking and dynamics studies of substituted 1,2,4-oxadiazole analogues against Mycobacterium tuberculosis

The alarming increase in multi- and extensively drug-resistant (MDR and XDR) strains of Mycobacterium tuberculosis (MTB) has triggered the scientific community to search for novel, effective, and safer therapeutics. To this end, a series of 3,5-disubstitu

One-potCuAAC synthesis of (1H-1,2,3-triazol-1-yl)methyl-1,3,4/1,2,4-oxadiazoles starting from available chloromethyl-1,3,4/1,2,4-oxadiazoles

The one-pot CuAAC synthesis of (1H-1,2,3-triazol-1-yl)methyl-1,3,4-oxadiazole and (1H-1,2,3-triazol-1-yl)methyl-1,2,4-oxadiazole derivatives via three-component reaction of consequent nucleophilic substitution of chlorine, with azide, and its further “cli

Isothiazolinone compound and corresponding application

The invention provides an isothiazolinone compound with an IDO inhibitory activity, and a preparing method and pharmaceutical application thereof. The invention particularly relates to a compound shown in a formula I, pharmaceutically acceptable salts thereof, isomers and prodrugs, wherein definitions of all groups are shown in the description. The invention further relates to compound drug preparations, drug compositions and the application of the compound drug preparations and the drug compositions in treating, relieving and/or preventing various relevant diseases caused by immunosuppressionsuch as tumors, virus infection or autoimmune diseases. The isothiazolinone compound has the excellent IDO inhibitory activity.