1823-48-9

Basic information

• Product Name: Phenol, 2,2'-[2,6-pyridinediylbis(methylidynenitrilo)]bis-
• CAS NO: 1823-48-9
• Molecular Formula: C19H15N3O2
• Molecular Weight: 317.347
• Mol File: 1823-48-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Phenol, 2,2'-[2,6-pyridinediylbis(methylidynenitrilo)]bis-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2,2'-[2,6-pyridinediylbis(methylidynenitrilo)]bis-(1823-48-9)
• EPA Substance Registry System: Phenol, 2,2'-[2,6-pyridinediylbis(methylidynenitrilo)]bis-(1823-48-9)

Safety Data

• Hazardous Substances Data: 1823-48-9(Hazardous Substances Data)

Upstream product

• 499-83-2 Pyridine-2,6-dicarboxylic acid 
• 5453-67-8 2,6-bis(methoxycarbonyl)pyridine 
• 5431-44-7 2,6-Pyridinedicarboxaldehyde 
• 95-55-6 2-amino-phenol 

Downstream Products

• 850209-88-0 [Cu(2,6-pyridinedicarboxaldehydebis(o-hydroxyphenylimine))(2-aminopyridine)Cl₂]*H₂O 
• 850209-86-8 [Co(2,6-pyridinedicarboxaldehydebis(o-hydroxyphenylimine))(2-aminopyridine)Br₂] 
• 889061-84-1 [Cu(2,6-pyridinedicarboxaldehydebis(o-hydroxyphenylimine))Cl₂] 
• 889061-82-9 [Co(2,6-pyridinedicarboxaldehydebis(o-hydroxyphenylimine))Cl₂] 
• 888954-16-3 [Zn(2,6-pyridinedicarboxaldehydebis(o-hydroxyphenylimine))Br] 
• 850209-89-1 [Zn(2,6-pyridinedicarboxaldehydebis(o-hydroxyphenylimine))(2-aminopyridine)Br₂] 

Relevant articles and documents

Synthesis and Magnetic Properties of Two-Step-Coordination Schiff Base Clusters

A new family of paramagnetic coordination compounds based on a diimine-pyridine pincer ligand has been prepared, using a two-step synthetic approach. The sequential introduction of identical or different transition metals (Co, Mn, Ni, Zn) afforded mono-,

Immobilized into montmorillonite Mn(II) complexes of novel pyridine schiff-base ligands and their catalytic reactivity in epoxidation of cyclohexene with O2

Mild temperature and atmospheric oxygen pressure assisted epoxidation of cyclohexene was achieved with a series of novel montmorillonite-supported Mn(II) complexes of pyridine Schiff-base ligands. The catalysts were characterized by IR, UV-Vis DRS, XRD, SEM and ICP. The heterogeneous catalysts were proved to promote the epoxidation of cyclohexene efficiently, affording the desired product epoxycyclohexane with a yield up to 92 %. The effects of various reaction conditions on the catalytic reaction were optimized. Repeated runs indicated that the catalysts were stable for 3 cycles without noticeable loss of their catalytic activity.

Heptacoordinate tin(IV) compounds derived from pyridine schiff bases: Synthesis, characterization, in Vitro cytotoxicity, anti-inflammatory and antioxidant activity

Tin(IV) complexes 2a-q derived from pyridine Schiff bases were prepared and characterized. Four complexes of this series were evaluated in vitro against different carcinogenic cell lines; besides their anti-inflammatory and antioxidant properties were also tested. Combination of mass spectrometry, multinuclear NMR and X-ray diffraction techniques evidenced the formation of heptacoordinated monomeric species. The X-ray diffraction analysis of 2a, 2b, 2i, 2j and 2n led to establish the heptacoordination around the tin atom in solid state and also revealed that the ligand occupies the equatorial positions of the distorted pentagonal bipyramidal geometry and the two alkyl or aryl groups the axial positions. The in-vitro study for complexes 2a-d against six tumor cell lines showed varied antiproliferative activity, the IC50 for all tested complexes was lower than that of the cis-platin. Compounds 2a-d also exhibited anti-inflammatory activity where complex 2c resulted to be more active (IC50=0.11 μm) than the indomethacin IC50=0.27 μm which was used as reference. The antioxidant activity in rat brain homogenate on inhibition of thiobarbituric acid reactive substances (TBARS) indicated that 2c (IC50=1.77 μm) is more active than the quercetine (4.11 μm) and α-tocopherol (IC50=569.09 μm).