1826-19-3

Basic information

• Product Name: 4-(4-METHYLPHENYL)-1,3-THIAZOLE
• Synonyms: 4-(4-METHYLPHENYL)-1,3-THIAZOLE;4-(P-TOLYL)THIAZOLE
• CAS NO: 1826-19-3
• Molecular Formula: C₁₀H₉NS
• Molecular Weight: 175.25016
• Mol File: 1826-19-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(4-METHYLPHENYL)-1,3-THIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-METHYLPHENYL)-1,3-THIAZOLE(1826-19-3)
• EPA Substance Registry System: 4-(4-METHYLPHENYL)-1,3-THIAZOLE(1826-19-3)

Safety Data

• Hazardous Substances Data: 1826-19-3(Hazardous Substances Data)

Upstream product

• 115-08-2 thiocarboxamide 
• 619-41-0 4-(bromoacetyl)toluene 
• 220222-34-4 3-Isopropoxy-4-p-tolyl-3H-thiazole-2-thione 
• 5720-05-8 4-methylphenylboronic acid 
• 34259-99-9 4-bromo-1,3-thiazole 

Downstream Products

• 125256-00-0 2-(2-propylpyridin-4-yl)-4-p-tolylthiazole 
• 2103-89-1 2-methylmercapto-4-(4'-methylphenyl)thiazole 

Relevant articles and documents

-

-

Nickel-catalyzed Suzuki-Miyaura couplings in green solvents

The nickel-catalyzed Suzuki-Miyaura coupling of aryl halides and phenol-derived substrates with aryl boronic acids using green solvents, such as 2-Me-THF and tert-amyl alcohol, is reported. This methodology employs the commercially available and air-stable precatalyst, NiCl2(PCy 3)2, and gives biaryl products in synthetically useful to excellent yields. Using this protocol, bis(heterocyclic) frameworks can be assembled efficiently.