182616-53-1

Basic information

• Product Name: PhP(m-xylyl)2
• Synonyms: PhP(m-xylyl)2
• CAS NO: 182616-53-1
• Molecular Weight: 318.398
• Mol File: 182616-53-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: PhP(m-xylyl)2(CAS DataBase Reference)
• NIST Chemistry Reference: PhP(m-xylyl)2(182616-53-1)
• EPA Substance Registry System: PhP(m-xylyl)2(182616-53-1)

Safety Data

• Hazardous Substances Data: 182616-53-1(Hazardous Substances Data)

Upstream product

• 22445-41-6 3,5-dimethylphenyl iodide 
• 638-21-1 phenylphosphane 

Relevant articles and documents

Water soluble phosphines VIII. Palladium-catalyzed P-C cross coupling reactions between primary or secondary phosphines and functional aryliodides - A novel synthetic route to water soluble phosphines

Tertiary phosphines Ph2P-Ar and PhP(Ar)2 containing mono-and disubstituted aromatic ring systems Ar (Ar = C6H4-X and C6H3-XY; X, Y = Me, OH, NH2, COOH, COOMe and SO3Na) are accessible in good yields by Pd(0)-catalyzed cross coupling reactions between diphenylphosphine or phenylphosphine and substituted aryliodides I-C6H4-X or I-C6H3-XY in organic solvents (dimethylacetamide, acetonitrile, methanol) using organic amines or potassium and sodium acetate as bases. If the primary phosphine is employed in the appropriate stoichiometric ratio, functionalized secondary phosphines, e.g. Ph(H)P-C6H4-p-SO3Na, may be obtained selectively.