182869-25-6

Basic information

• Product Name: 1-(2,4-difluorophenyl)-7-(3,5-dimethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
• CAS NO: 182869-25-6
• Molecular Formula: C₂₁H₁₉F₃N₄O₃
• Molecular Weight: 432.3958
• Mol File: 182869-25-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 618.8°C at 760 mmHg
• Flash Point: 328°C
• Density: 1.414g/cm³
• Vapor Pressure: 3.6E-16mmHg at 25°C
• Refractive Index: 1.591
• CAS DataBase Reference: 1-(2,4-difluorophenyl)-7-(3,5-dimethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4-difluorophenyl)-7-(3,5-dimethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid(182869-25-6)
• EPA Substance Registry System: 1-(2,4-difluorophenyl)-7-(3,5-dimethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid(182869-25-6)

Safety Data

• Hazardous Substances Data: 182869-25-6(Hazardous Substances Data)

Usage

Description

1-(2,4-difluorophenyl)-7-(3,5-dimethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid is a synthetic compound that belongs to the class of quinolone antibiotics. It is characterized by its potent antibacterial activity and a unique chemical structure that includes a naphthyridine core with various functional groups such as fluorine, phenyl, piperazine, and carboxylic acid moieties. 1-(2,4-difluorophenyl)-7-(3,5-dimethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid is known for its ability to inhibit bacterial DNA gyrase and topoisomerase IV, which are crucial enzymes for DNA replication and repair in bacteria, ultimately disrupting their DNA synthesis and leading to cell death.

Uses

Used in Pharmaceutical Industry:
1-(2,4-difluorophenyl)-7-(3,5-dimethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid is used as an active pharmaceutical ingredient for the development of antibiotics. Its potent antibacterial properties make it effective in treating a wide range of bacterial infections, providing a valuable treatment option for patients suffering from such conditions.
Used in Research and Development:
In the field of scientific research, this compound serves as a valuable tool for studying the mechanisms of bacterial resistance and the development of new antibiotics. Its unique structure and mode of action can provide insights into the design of novel antimicrobial agents, potentially leading to the discovery of more effective treatments for bacterial infections.
Used in Veterinary Medicine:
1-(2,4-difluorophenyl)-7-(3,5-dimethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid can also be utilized in veterinary medicine for the treatment of bacterial infections in animals. Its broad-spectrum antibacterial activity makes it a suitable candidate for use in veterinary antibiotics, helping to maintain the health of livestock and pets.
Used in Drug Resistance Studies:
1-(2,4-difluorophenyl)-7-(3,5-dimethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid's ability to inhibit bacterial DNA gyrase and topoisomerase IV makes it an important subject of study in understanding the development of antibiotic resistance. By examining the interactions between this compound and bacterial enzymes, researchers can gain a better understanding of the mechanisms behind resistance and work towards developing strategies to combat it.