182967-41-5

Basic information

• Product Name: (S)-2-(3,5-Dimethyl-pyrazole-1-carbonyl)-pyrrolidine-1-carboxylic acid benzyl ester
• Synonyms: (S)-2-(3,5-Dimethyl-pyrazole-1-carbonyl)-pyrrolidine-1-carboxylic acid benzyl ester
• CAS NO: 182967-41-5
• Molecular Weight: 327.383
• Mol File: 182967-41-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-(3,5-Dimethyl-pyrazole-1-carbonyl)-pyrrolidine-1-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(3,5-Dimethyl-pyrazole-1-carbonyl)-pyrrolidine-1-carboxylic acid benzyl ester(182967-41-5)
• EPA Substance Registry System: (S)-2-(3,5-Dimethyl-pyrazole-1-carbonyl)-pyrrolidine-1-carboxylic acid benzyl ester(182967-41-5)

Safety Data

• Hazardous Substances Data: 182967-41-5(Hazardous Substances Data)

Upstream product

• 67-51-6 3,5-dimethyl-1H-pyrazole 
• 1148-11-4 N-Benzyloxycarbonyl-L-proline 

Downstream Products

• 182967-38-0 (S)-2-{2-[(S)-1-((S)-2-Benzyloxycarbonylamino-3-phenyl-propionyl)-pyrrolidin-2-yl]-2-oxo-acetylamino}-4-methyl-pentanoic acid tert-butyl ester 
• 182967-36-8 (R)-2-{2-[(S)-1-((S)-2-Benzyloxycarbonylamino-3-phenyl-propionyl)-pyrrolidin-2-yl]-2-oxo-acetylamino}-4-methyl-pentanoic acid tert-butyl ester 
• 72351-45-2 2-Hydroxy-2-(N-benzyloxycarbonylpyrrolidin-2-yl)-acetic acid 
• 182758-72-1 2-(Cyano-hydroxy-methyl)-pyrrolidine-1-carboxylic acid benzyl ester 
• 72351-44-1 2-Hydroxy-2-(L-pyrrolidin-2-yl)acetic acid 
• 182967-35-7 (S)-2-[(R)-2-(2-{(S)-1-[(S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylamino)-3-methyl-butyryl]-pyrrolidin-2-yl}-2-oxo-acetylamino)-4-methyl-pentanoylamino]-3-methyl-butyric acid benzyl ester 
• 182758-54-9 (R)-2-{2-[(S)-1-((S)-2-Benzyloxycarbonylamino-3-phenyl-propionyl)-pyrrolidin-2-yl]-2-oxo-acetylamino}-3-phenyl-propionic acid tert-butyl ester 

Relevant articles and documents

Poststatin, a new inhibitor of prolyl endopeptidase. VI. Endopeptidase inhibitory activity of poststatin analogues containing pyrrolidine ring

Several pyrrolidine-containing analogues of poststatin were synthesized and examined for their inhibitory activity against prolyl endopeptidase and cathepsin B in vitro. Replacement of the postine residue with 2-oxo-2-(2-pyrrolidinyl)acetic acid increased the selectivity and inhibitory activity against prolyl endopeptidase. Benzyloxycarbonyl-L-phenylalanyl-(S)-2-oxo-2-(2-pyrrolidinyl)acetyl -D-phenylalanine was about 46 times as active to prolyl endopeptidase as natural poststatin.