18321-15-8

Basic information

• Product Name: 1,2-dithiane 1,1-dioxide
• Synonyms: 1,2-Dithiane 1,1-dioxide; 1,2-dithiane, 1,1-dioxide; 1,2-Dithiane-1,1-dioxide
• CAS NO: 18321-15-8
• Molecular Formula: C₄H₈O₂S₂
• Molecular Weight: 152.2351
• Mol File: 18321-15-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 336.1°C at 760 mmHg
• Flash Point: 157.1°C
• Density: 1.353g/cm³
• Vapor Pressure: 0.000223mmHg at 25°C
• Refractive Index: 1.54
• CAS DataBase Reference: 1,2-dithiane 1,1-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-dithiane 1,1-dioxide(18321-15-8)
• EPA Substance Registry System: 1,2-dithiane 1,1-dioxide(18321-15-8)

Safety Data

• Hazardous Substances Data: 18321-15-8(Hazardous Substances Data)

Usage

Type of compound

Heterocyclic organic compound

Structure

Six-membered ring containing oxygen and sulfur atoms

Applications

a. Building block in organic synthesis
b. Formation of cyclic sulfones
c. Protecting group in organic chemistry reactions
d. Reagent in the synthesis of pharmaceuticals and agrochemicals

Production method

Oxidation of 1,2-dithiole

Stability

High stability due to its structure

Compatibility

Compatible with a variety of chemical reactions

Role

Crucial in the development of various organic molecules

Industries

Pharmaceutical and agricultural industries

Upstream product

• 505-20-4 1,2-dithiane 
• 101010-00-8 Sodium 4-(p-chlorophenyldithio)butanesulfinate 
• 101009-99-8 Sodium 4-(p-methoxyphenyldithio)butanesulfinate 
• 101010-01-9 Sodium; 4-(3,4-dichloro-phenyldisulfanyl)-butane-1-sulfinate 
• 101010-02-0 Sodium; 4-(2,6-dichloro-phenyldisulfanyl)-butane-1-sulfinate 

Downstream Products

• 19293-56-2 Natrium-4-<2-acetamido-aethyl-dithio>-butansulfinat 
• 101009-99-8 Sodium 4-(p-methoxyphenyldithio)butanesulfinate 
• 101010-01-9 Sodium; 4-(3,4-dichloro-phenyldisulfanyl)-butane-1-sulfinate 
• 101010-02-0 Sodium; 4-(2,6-dichloro-phenyldisulfanyl)-butane-1-sulfinate 
• 111848-91-0 Sodium; 4-(2,4,6-trimethoxy-phenyldisulfanyl)-butane-1-sulfinate 
• 62911-23-3 Sodium; 4-p-tolyldisulfanyl-butane-1-sulfinate 
• 101010-00-8 Sodium 4-(p-chlorophenyldithio)butanesulfinate 
• 120586-50-7 1,2-dithiane-(4R,5S-dihydroxy)-1,1-dioxide 

Relevant articles and documents

Geometry-dependent quenching of singlet oxygen by dialkyl disulfides

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Organic Disulfides and Related Substances. 45. Synthesis and Properties of Some Disulfide Sulfinate Salts Containing No Nitrogen

Disulfide sulfinates of the structure RSS(CH2)4SO2Na were synthesized by reaction of 1,2-dithiane 1,1-dioxide (1), thiols, and sodium methoxide in methanol.Disproportionation was minimized by precipitating and reprecipitating the products with ether as quickly as possible; where R = aryl, protection from light is advisable.The groups R typify large lipophilic ones (n-decyl, 1-adamantyl), small hydrophilic ones (2-carboxyethyl, 2,3-dihydroxypropyl), disulfide sulfinates , and aryl groups substituted by electron-donating or electron-withdrawing groups.The products usually were quite hygroscopic and were isolated as hydrates.They disproportionated with varying ease in aqueous solution either to 1 or to the two symmetrical disulfides, RSSR and NaO2S(CH2)4SS(CH2)4SO2Na.