183254-49-1

Basic information

• Product Name: 1-cyclopropyl-7-(3-ethylpiperazin-1-yl)-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
• CAS NO: 183254-49-1
• Molecular Formula: C₁₉H₂₁F₂N₃O₃
• Molecular Weight: 377.3851
• Mol File: 183254-49-1.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 573.7°C at 760 mmHg
• Flash Point: 300.7°C
• Density: 1.405g/cm³
• Vapor Pressure: 5.33E-14mmHg at 25°C
• Refractive Index: 1.605
• CAS DataBase Reference: 1-cyclopropyl-7-(3-ethylpiperazin-1-yl)-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-cyclopropyl-7-(3-ethylpiperazin-1-yl)-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid(183254-49-1)
• EPA Substance Registry System: 1-cyclopropyl-7-(3-ethylpiperazin-1-yl)-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid(183254-49-1)

Safety Data

• Hazardous Substances Data: 183254-49-1(Hazardous Substances Data)

Usage

Chemical class

Quinolone antibiotics

Function

Inhibit DNA replication and repair enzymes in bacteria

Structure

Cyclopropyl group
3-ethylpiperazin-1-yl moiety
6,8-difluoro substituents
4-oxo-1,4-dihydroquinoline core
3-carboxylic acid functional group

Potency

Enhanced by cyclopropyl group and difluoro substituents

Spectrum of activity

Broadened by cyclopropyl group and difluoro substituents

Pharmacokinetic profile

Improved by ethylpiperazinyl moiety

Antimicrobial efficacy

Enhanced by ethylpiperazinyl moiety

Applications

Treatment of various bacterial infections, particularly fluoroquinolone-resistant strains