18328-00-2

Basic information

• Product Name: Benzenepropanenitrile, 2-cyano-
• CAS NO: 18328-00-2
• Molecular Formula: C10H8N2
• Molecular Weight: 156.187
• Mol File: 18328-00-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzenepropanenitrile, 2-cyano-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanenitrile, 2-cyano-(18328-00-2)
• EPA Substance Registry System: Benzenepropanenitrile, 2-cyano-(18328-00-2)

Safety Data

• Hazardous Substances Data: 18328-00-2(Hazardous Substances Data)

Upstream product

• 128-08-5 N-Bromosuccinimide 
• 24532-97-6 (+/-)-3t-(cis-2-cyano-cyclohex-3-enyl)-acrylonitrile 
• 71-43-2 benzene 
• 22115-41-9 2-(bromomethyl)benzonitrile 
• 590-17-0 cyanomethyl bromide 

Downstream Products

• 19971-23-4 3-<2-Hydroxyamidino-phenyl>-propionsaeureamidoxim 
• 776-79-4 2-(2-carboxyethyl)benzoic acid 

Relevant articles and documents

Radical cyclisation onto nitriles

Iminyl radicals, generated by 5-exo cyclisation of alkyl, vinyl and aryl C-centred radicals onto nitriles, undergo β-scission (nitrile translocation), reduction or tandem cyclisation onto alkenes depending on the nature of the α-substituent. 5-exo Cyclisations of aryl radicals onto nitriles undergo nitrile translocation when the α-substituent is CN, CO2R, SO2Ph or CONMe2. The rate of translocation is faster than 5- or 6-exo cyclisation onto alkenes or 1,5-hydrogen abstraction of allylic hydrogens. When the α-substituents are alkyl, the intermediate iminyl radicals do not undergo nitrile translocation. (C) 2000 Elsevier Science Ltd.