183312-49-4

Basic information

• Product Name: Benzenemethanol, a-ethynyl-2-(phenylethynyl)-
• CAS NO: 183312-49-4
• Molecular Formula: C17H12O
• Molecular Weight: 232.282
• Mol File: 183312-49-4.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, a-ethynyl-2-(phenylethynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, a-ethynyl-2-(phenylethynyl)-(183312-49-4)
• EPA Substance Registry System: Benzenemethanol, a-ethynyl-2-(phenylethynyl)-(183312-49-4)

Safety Data

• Hazardous Substances Data: 183312-49-4(Hazardous Substances Data)

Upstream product

• 6630-33-7 ortho-bromobenzaldehyde 
• 59046-72-9 o-(phenylethynyl)benzaldehyde 
• 74-86-2 acetylene 
• 536-74-3 phenylacetylene 
• 65032-27-1 ethynylmagnesium chloride 
• 879286-37-0 3-(trimethylsilyl)-1-[2-(2-phenylethynyl)phenyl]prop-2-yn-1-ol 
• 4301-14-8 acetylenemagnesium bromide 

Downstream Products

• 1215270-11-3 C₂₀H₁₆O 
• 1215270-12-4 C₂₄H₂₂O 
• 1215270-09-9 C₂₄H₁₈O 
• 1215270-06-6 1-[2-(2-phenylethynyl)phenyl]-prop-2-ynyl methyl ether 
• 1280219-86-4 3-(4-bromophenyl)-1-(2-(phenylethynyl)phenyl)prop-2-yn-1-ol 
• 1280219-97-7 (3-methyl-10-phenylphenanthren-4-yl)(thien-2-yl)methanone 
• 1393090-11-3 methyl 1-(2-(phenylethynyl)phenyl)-3-(3-(trifluoromethyl)phenyl)-prop-2-ynyl carbonate 
• 1393090-40-8 1-(2-(phenylethynyl)phenyl)-3-(3-(trifluoromethyl)phenyl)prop-2-yn-1-ol 
• 1394325-10-0 C₁₀H₆(Sn(C₄H₉)3)C(O)C₆H₅ 
• 644-13-3 C₆H₅COC₁₀H₇ 

Relevant articles and documents

Synthetic method 1-2 -dihydrocyclobutene [a] naphthalene derivative and precursor thereof

The invention relates to the field of organic synthetic chemistry, in particular to a 1,2-dihydrocyclobuteno[a] naphthalene derivative and a synthesis method of a precursor thereof. The invention provides a synthesis method of allenic ketone ester. According to the synthesis method, benzene ring-connected dieneyne ketone ester is synthesized for the first time; the dieneyne ketone ester is the precursor for synthesizing the 1,2-dihydrocyclobuteno[a] naphthalene, and has the advantages of being simple, convenient, efficient, mild in reaction condition, environmentally friendly, low in cost, low energy in consumption and the like.

A Silver-Catalyzed Modular Intermolecular Access to 6,6-Spiroketals

A modular synthesis of 6,6-spiroketals via silver catalysis is reported. By combining an intermolecular Michael addition and a 6-endo-dig cyclization, this cascade reaction allows the modular preparation of highly substituted 6,6-spiroketals by combining two substrate molecules. Established methods accessing this interesting substructure are complemented by this new transformation. The protocol tolerates diverse substitution patterns and functional groups. (Figure presented.).

Merging [2+2] Cycloaddition with Radical 1,4-Addition: Metal-Free Access to Functionalized Cyclobuta[a]naphthalen-4-ols

A metal-free [2+2] cycloaddition and 1,4-addition sequence induced by S-centered radicals has been achieved by treating benzene-linked allene-ynes with aryldiazonium tetrafluoroborates and DABCO-bis(sulfur dioxide) in a one-pot procedure. The reaction provides a greener and more practical access to functionalized cyclobuta[a]naphthalen-4-ols with valuable applications. More than 50 examples are demonstrated with excellent diastereoselectivity and chemical yields. The reaction pathway is proposed to proceed by the following steps:[2+2] cycloaddition, insertion of SO2, 1,4-addition, diazotization, and tautomerization.