183318-41-4Relevant articles and documents
Synthesis of (2S,5S)-5-fluoromethylornithine; a potent inhibitor of ornithine aminotransferase
Ducep,Heintzelmann,Jund,Lesur,Schleimer,Zimmermann
, p. 327 - 335 (2007/10/03)
Only one of the four enantiomers of 5-fluoromethylornithine 1 was an irreversible inhibitor of ornithine aminotransferase. The active enantiomer la was synthesized from diaminoadipic acid 2 with a chemical diastereomeric separation and an enantiomeric res