18354-56-8

Basic information

• Product Name: 1-(thieno[2,3-b]pyridin-2-yl)ethanone
• CAS NO: 18354-56-8
• Molecular Formula: C₉H₇NOS
• Molecular Weight: 177.223
• Mol File: 18354-56-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 318.3°C at 760 mmHg
• Flash Point: 146.3°C
• Density: 1.286g/cm³
• Vapor Pressure: 0.000365mmHg at 25°C
• Refractive Index: 1.655
• CAS DataBase Reference: 1-(thieno[2,3-b]pyridin-2-yl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(thieno[2,3-b]pyridin-2-yl)ethanone(18354-56-8)
• EPA Substance Registry System: 1-(thieno[2,3-b]pyridin-2-yl)ethanone(18354-56-8)

Safety Data

• Hazardous Substances Data: 18354-56-8(Hazardous Substances Data)

Usage

Description

1-(thieno[2,3-b]pyridin-2-yl)ethanone is a chemical compound characterized by its molecular formula C11H9NO. It is a yellow to brown solid with a strong odor and is widely utilized in research and laboratory settings. 1-(thieno[2,3-b]pyridin-2-yl)ethanone is a ketone derivative that features a thieno[2,3-b]pyridine ring system, which is recognized for its diverse biological activities. The unique structural features of 1-(thieno[2,3-b]pyridin-2-yl)ethanone contribute to its potential applications in various fields, including medicinal chemistry, drug discovery, and the synthesis of organic compounds.

Uses

Used in Pharmaceutical and Agrochemical Industries:
1-(thieno[2,3-b]pyridin-2-yl)ethanone is used as a key intermediate in the production of pharmaceuticals and agrochemicals. Its unique structural features and chemical properties make it a valuable building block for the synthesis of novel compounds with potential applications in these industries.
Used in Medicinal Chemistry and Drug Discovery:
1-(thieno[2,3-b]pyridin-2-yl)ethanone is employed as a valuable compound in the field of medicinal chemistry and drug discovery. Its diverse biological activities and unique structural features make it a promising candidate for the development of new drugs and therapeutic agents.
Used in Research and Laboratory Settings:
1-(thieno[2,3-b]pyridin-2-yl)ethanone is utilized as a research compound in various laboratory settings. Its strong odor and distinct properties make it an interesting subject for scientific investigations and the development of new methodologies and techniques in the field of chemistry.
Used in the Synthesis of Organic Compounds:
1-(thieno[2,3-b]pyridin-2-yl)ethanone is used as a building block in the synthesis of various organic compounds. Its reactivity and unique structural features make it a valuable component for the creation of novel molecules with potential applications in different industries.

Upstream product

• 28988-21-8 3-bromanylthieno[2,3-b]pyridine 
• 127-19-5 N,N-dimethyl acetamide 
• 36404-88-3 2-chloro-3-carbaldehydepyridine 
• 24653-75-6 1-mercaptopropan-2-one 
• 122-31-6 malondialdehyde bis(diethyl acetal) 
• 113975-22-7 2-fluoro-3-iodopyridine 

Relevant articles and documents

Straightforward synthesis of 2-acetyl-substituted benzo[b]thiophenes

Described herein is a green one-step protocol for the preparation of substituted 2-acetylbenzo[b]thiophenes from commercially available aromatic halides. This efficient method has the advantage of using water as the reaction medium, resulting in a high yield of pure cyclized products. Two scaffold types have been prepared using this general procedure: 2-acetylbenzo[b]thiophenes and 2-acetyl-3-aminobenzo[b]thiophenes, both crystallized directly from the reaction mixture, due to their low solubility with water, and without the need for an additional purification step. Georg Thieme Verlag Stuttgart · New York.

Method for synthesizing 2-carbonyl thienopyridine compound

The invention discloses a method for synthesizing 2-carbonyl thienopyridine compound. According to the method provided by the invention, 2-halo-3-alkynol pyridine as shown in formula (I) and sulfur sources are mixed; and with the aid of a catalyst, after reacting in a solvent for a while, 2-carbonyl thienopyridine compound as shown in formula (II) is prepared after purification treatment. The sulfur sources are selected from one or more of elemental sulphur, ammonium sulfide, thiourea, sodium sulfide, and ethyl potassium xanthate, and the catalyst is selected from one of copper acetate, cuprous iodide, cuprous bromide, cuprous chloride, copper chloride, cupric acetylacetonate, palladium chloride, and copper trifluoromethanesulfonate. The technical scheme of the invention has the advantagesof less reaction steps, simple operation method, wide source of reaction substrate, low costs and easy availability of the catalyst, high product yield and the like, and the technical scheme is verysuitable for industrial mass production. The formulas are shown in the description.

DIHYDROISOXAZOLE COMPOUNDS, PARASITICIDAL USES AND FORMULATIONS THEREOF

Provided are dihydroisoxazole compounds useful for controlling parasites both in animals and agriculture. Further provided are methods for controlling parasite infestations of an animal by administering an effective amount of a compound as described above, or a pharmaceutically acceptable salt thereof, to an animal, as well as formulations for controlling parasite infestations using the compounds described above or an acceptable salt thereof, and an acceptable carrier.