183550-95-0

Basic information

• Product Name: 3-Pyridinecarboxamide, N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-chloro-N-(2-hydroxyethyl)-4- phenyl-
• CAS NO: 183550-95-0
• Molecular Formula: C23H17ClF6N2O2
• Molecular Weight: 502.844
• Mol File: 183550-95-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-Pyridinecarboxamide, N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-chloro-N-(2-hydroxyethyl)-4- phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarboxamide, N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-chloro-N-(2-hydroxyethyl)-4- phenyl-(183550-95-0)
• EPA Substance Registry System: 3-Pyridinecarboxamide, N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-chloro-N-(2-hydroxyethyl)-4- phenyl-(183550-95-0)

Safety Data

• Hazardous Substances Data: 183550-95-0(Hazardous Substances Data)

Upstream product

• 156241-24-6 2-[[3,5-bis(trifluoromethyl)benzyl]amino]-1-ethanol 
• 183551-51-1 3,5-bis(trifluoromethyl)benzyl methanesulfonate 
• 32707-89-4 3,5-bis(trifluoromethyl)benzenemethanol 

Relevant articles and documents

Amide-based atropisomers in tachykinin NK1-receptor antagonists: Synthesis and antagonistic activity of axially chiral N-benzylcarboxamide derivatives of 2,3,4,5-tetrahydro-6H-pyrido[2,3-b][1,5]oxazocin-6-one

A series of novel N-benzylcarboxamide derivatives of bicyclic compounds, 3,4-dihydropyrido[3,2-f][1,4]oxazepin-5(2H)-one and 2,3,4,5-tetrahydro-6H- pyrido[2,3-b][1,5]oxazocin-6-one, were synthesized by cyclization of N-benzyl-2-chloro-N-(2-hydroxyethyl)-

CYCLIC COMPOUNDS, THEIR PRODUCTION AND USE

Novel compounds of the following general formula or salts thereof. STR1 wherein Ring M is a heterocyclic ring having--N=C ,--CO--N or--CS--N as the partial structure--X . . . Y ; R. sup.a and R. sup.b are bonded to each other to form Ring A, or they are the same or different and represent, independently, a hydrogen atom or a substituent on the Ring M; Ring A and Ring B represent, independently, an optionally substituted homocyclic or heterocyclic ring, and at least one of them is optionally substituted heterocyclic ring; Rng C is optionally substituted homocyclic or heterocyclic ring; Rng Z is an optionally substituted ring; and n represents an integer of from 1 to 6, or a salt thereof, which has anexcellent tachykinin receptor antagonistic effect, and their production, and pharmaceutical compositions.