18362-30-6Relevant articles and documents
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Bunnett et al.
, p. 2512,2513 (1961)
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Postmus,C. et al.
, p. 2693 - 2698 (1964)
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A Strategy toward Icetexane Natural Products
Moon, Daniel J.,Al-Amin, Mohammad,Lewis, Robert S.,Arnold, Kimberly M.,Yap, Glenn P. A.,Sims-Mourtada, Jennifer,Chain, William J.
supporting information, p. 3348 - 3351 (2018/07/13)
Icetexane diterpenoids are richly complex polycyclic natural products that have been described with a variety of biological activities. We report here a general synthetic approach toward the 6-7-6 tricyclic core structure of these interesting synthetic ta
Pd-Catalyzed Ortho C-H Hydroxylation of Benzaldehydes Using a Transient Directing Group
Chen, Xiao-Yang,Ozturk, Seyma,Sorensen, Erik J.
supporting information, p. 6280 - 6283 (2017/12/08)
The direct Pd-catalyzed ortho C-H hydroxylation of benzaldehydes was achieved using 4-chloroanthranilic acid as the transient directing group, 1-fluoro-2,4,6-trimethylpyridnium triflate as the bystanding oxidant, and p-toluenesulfonic acid as the putative oxygen nucleophile. The unusual C-H chlorination and polyfluoroalkoxylation reactions signaled the importance of external nucleophiles to the outcome of Pd(IV) reductive eliminations.