18362-80-6Relevant articles and documents
Influence of vehicles on antioxidant efficacy in hair
Rubio,Alonso,Martí,Martínez,Coderch
, p. 15929 - 15936 (2016)
The UV radiation of sunlight is known to damage human hair, causing fibre degradation. Gallic acid (GA) was used as an active principle because of its antioxidant properties, which confer protection against free radicals. Encapsulation technologies, such
Fluorescent probes for hydrogen peroxide based on a non-oxidative mechanism
Maeda, Hatsuo,Fukuyasu, Yuka,Yoshida, Shoko,Fukuda, Masako,Saeki, Kanako,Matsuno, Hiromi,Yamauchi, Yuji,Yoshida, Kenji,Hirata, Kazumasa,Miyamoto, Kazuhisa
, p. 2389 - 2391 (2004)
Highly selective detection of H2O2 through a non-oxidative mechanism has been achieved by desulfonylation of 1 to the corresponding fluorescein, This approach has been used for the intracellular formation of H2O2/sub
FLUOROMETER FOR FLOW INJECTION ANALYSIS WITH APPLICATION TO OXIDASE ENZYME DEPENDENT REACTIONS.
Kelly,Christian
, p. 2110 - 2114 (1981)
A simple effective flow fluorometer has been assembled and operated in conjunction with a flow injection analysis (FIA) system. A submicroliter capillary sheath flow cell is used for fluorescence detection with a laser source. The instrument has been test
Water-Soluble Nanoparticles with Twisted Double [7]Carbohelicene for Lysosome-Targeted Cancer Photodynamic Therapy
Zhao, Hao,Xu, Xiushang,Zhou, Long,Hu, Yunbin,Huang, Yiming,Narita, Akimitsu
, (2021/11/10)
Helicene-based therapeutic agents for organelle-targeted photodynamic therapy (PDT) involving both type I and II are challenging and still underexplored. Herein, water-soluble nanoparticles containing twisted double [7]carbohelicene (D7H-NPs) are prepared
Coordination-Accelerated Radical Formation from Acyclic Enediynes for Tumor Cell Suppression
Li, Baojun,Zhang, Mengsi,Lu, Haotian,Ma, Hailong,Wang, Yue,Chen, Huimin,Ding, Yun,Hu, Aiguo
, p. 4352 - 4357 (2019/12/03)
A maleimide-based acyclic enediyne with salicylaldiminato substituents at the alkyne termini was synthesized, which was further chelated with three kinds of metal-ions, CuII, ZnII, and MgII, and form metalloenediynes. The cycloaromatization of this thermally inactive enediyne ligand was greatly accelerated through the coordination with metal ions. Specifically, the CuII-metalloenediyne showed an extremely low onset temperature of 55 °C and underwent spontaneous cycloaromatization at ambient temperature to produce free radicals, followed by generation of reactive oxygen species in the physiological environment. The metalloenediyne exhibited excellent DNA cleavage ability and high cytotoxicity towards HeLa cells, with half-maximal inhibitory concentration values comparable to many commercial antitumor agents. The combination of the electron-withdrawing effect of the maleimide moiety at the ene position and metal coordination at the yne termini provides a new inspiration for designing and synthesizing highly efficient enediyne antitumor agents.