183626-76-8 Usage
Description
Ipratropium Bromide Impurity E is a synthetic compound derived from Atropine (A794630), a naturally occurring nerve agent found in plants of the nightshade family. It is characterized by its chemical structure, which is a modification of the parent compound, Atropine.
Uses
Used in Pharmaceutical Industry:
Ipratropium Bromide Impurity E is used as an intermediate in the synthesis of Ipratropium Bromide, a medication commonly used for the treatment of asthma and chronic obstructive pulmonary disease (COPD). It acts as an anticholinergic agent, helping to relax the muscles in the airways and reduce inflammation.
Used in Research and Development:
Ipratropium Bromide Impurity E is also utilized in research and development for the study of its chemical properties, potential applications, and effects on the human body. This can lead to the discovery of new therapeutic uses or the development of novel drug candidates.
Used in Quality Control:
In the pharmaceutical manufacturing process, Ipratropium Bromide Impurity E can be used as a reference material for quality control purposes. It helps ensure the purity and consistency of the final product by providing a benchmark for comparison during testing and analysis.
Check Digit Verification of cas no
The CAS Registry Mumber 183626-76-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,3,6,2 and 6 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 183626-76:
(8*1)+(7*8)+(6*3)+(5*6)+(4*2)+(3*6)+(2*7)+(1*6)=158
158 % 10 = 8
So 183626-76-8 is a valid CAS Registry Number.
183626-76-8Relevant articles and documents
Synthesis of ipratropium bromide-related compounds
Tsyskovskaia, Irina,Kandil, Mustapha,Beaumier, Yves
, p. 439 - 446 (2007)
Synthesis of ipratropium bromide metabolites is described. Copyright Taylor & Francis Group, LLC.
Preparation method of ipratropium bromide
-
, (2017/06/14)
The invention relates to a preparation method of an M-choline receptor blocking agent of ipratropium bromide 1. The preparation method comprises the following steps of using ethyl phenylacetate as starting raw materials; performing reaction with isopropyl tropanol; generating phenylacetate isopropyl tropeine; then, performing substitution, reduction and addition reaction to obtain the ipratropium bromide. The method has the advantages that the operation is simple; safety and controllability are realized; the work protection is low; the preparation method is suitable for industrial production. The formula is shown as the accompanying drawing, and the molecular weight is 412.36.
