18369-83-0 Usage
Description
METHYL CHLOROTHIOLFORMATE is a chemical reagent with significant applications in the synthesis of various compounds, particularly those with biological and pharmaceutical importance.
Uses
Used in Pharmaceutical Industry:
METHYL CHLOROTHIOLFORMATE is used as a synthetic reagent for the production of Mitomycin C (M371900)-tethered phosphorothiaoate oligodeoxynucleotides, which serve as an anti-tumor antibiotic. This application is crucial in the development of treatments for cancer, as these oligodeoxynucleotides can help target and combat tumor growth.
Used in Agricultural Industry:
METHYL CHLOROTHIOLFORMATE is also used in the preparation of Brassinin (B676950) derivatives, which are plant metabolites with significant importance. Brassinin plays a dual role as an effective phytoalexin, providing plants with a natural defense against pathogens, and as an early biosynthetic precursor for the majority of phytoalexins. This application contributes to the development of more resilient and disease-resistant crops, ultimately benefiting the agricultural industry and food security.
Check Digit Verification of cas no
The CAS Registry Mumber 18369-83-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,3,6 and 9 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 18369-83:
(7*1)+(6*8)+(5*3)+(4*6)+(3*9)+(2*8)+(1*3)=140
140 % 10 = 0
So 18369-83-0 is a valid CAS Registry Number.
InChI:InChI=1/C2H3ClOS/c1-5-2(3)4/h1H3
18369-83-0Relevant articles and documents
Synthesis of amides from Glycosmis species: Methylthiopropenoic acid, methylsulfonylpropenoic acid, thiocarbamic acid S-methyl ester, and senecioic acid amides
Hinterberger, Sabine,Hofer, Otmar,Greger, Harald
, p. 487 - 496 (2007/10/03)
Representative samples of several types of naturally occurring amides from south and southeast Asian Glycosmis species were synthesized for proof of structures and for bioactivity testing. With one exception (senecioic acid) all these amides were characterized by sulfur containing acid components (methylthiopropenoic acid, methylsulfonylpropenoic acid, and thiocarbamic acid) in combination with phenethylamine derived amino moieties.
NOVEL SYNTHESIS OF DISUBSTITUTED THIOLCARBAMATES VIA A SULFUR TRANSFER AGENT-POTASSIUM ALKYL OR BENZYL DITHIOCARBONATES
D'Amico, John J.,Schafer, Tann
, p. 301 - 304 (2007/10/02)
The reaction of N,N-disubstituted carbamoyl chlorides with potassium alkyl or benzyl dithiocarbonates afforded a novel synthesis of disubstituted thiolcarbamates.