18371-72-7

Basic information

• Product Name: 1-Chloro-3-(decyloxy)-2-propanol
• Synonyms: 1-Chloro-3-(decyloxy)-2-propanol
• CAS NO: 18371-72-7
• Molecular Formula: C₁₃H₂₇ClO₂
• Molecular Weight: 250.81
• Mol File: 18371-72-7.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 340.8°C at 760 mmHg
• Flash Point: 159.9°C
• Appearance: /
• Density: 0.969g/cm³
• Vapor Pressure: 5.55E-06mmHg at 25°C
• Refractive Index: 1.456
• CAS DataBase Reference: 1-Chloro-3-(decyloxy)-2-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Chloro-3-(decyloxy)-2-propanol(18371-72-7)
• EPA Substance Registry System: 1-Chloro-3-(decyloxy)-2-propanol(18371-72-7)

Safety Data

• Hazardous Substances Data: 18371-72-7(Hazardous Substances Data)

Usage

Chlorinated alcohol

Contains a chlorine atom bonded to a hydrocarbon chain This makes 1-Chloro-3-(decyloxy)-2-propanol a derivative of alcohol with added chlorine.

Long alkyl chain

A chain of 10 carbon atoms (decyl) The presence of a long alkyl chain contributes to the compound's surfactant and emulsifying properties.

Hydroxyl group

An -OH group The presence of the hydroxyl group classifies the compound as an alcohol and enhances its solvation capabilities.

Surfactant

Reduces surface tension between liquids and solids This property allows 1-Chloro-3-(decyloxy)-2-propanol to be used in cleaning products and personal care items.

Emulsifier

Helps mix two immiscible substances (e.g., oil and water) The compound's surfactant properties enable it to create stable emulsions.

Solubilizer

Enhances the dissolution of various substances 1-Chloro-3-(decyloxy)-2-propanol is used in personal care and cleaning products to improve solubility.

Stabilizer

Maintains the consistency and uniformity of mixtures The compound helps to prevent separation and maintain stability in the products it is used in.

Intermediate in chemical synthesis

Used as a starting material to produce other chemicals 1-Chloro-3-(decyloxy)-2-propanol can be further modified or react with other chemicals to create new compounds.

Low toxicity

Considered to have minimal harmful effects on humans and the environment Despite its low toxicity, appropriate safety measures and regulations should be followed when handling 1-Chloro-3-(decyloxy)-2-propanol.

InChI:InChI=1/C13H27ClO2/c1-2-3-4-5-6-7-8-9-10-16-12-13(15)11-14/h13,15H,2-12H2,1H3

Upstream product

• 112-30-1 1-Decanol 
• 106-89-8 epichlorohydrin 

Downstream Products

• 3497-06-1 1-decyl glycidyl ether 
• 10430-97-4 glycerol 1-O-decylether 

Relevant articles and documents

Rational design 2-hydroxypropylphosphonium salts as cancer cell mitochondria-targeted vectors: Synthesis, structure, and biological properties

It has been shown for a wide range of epoxy compounds that their interaction with triphenylphosphonium triflate occurs with a high chemoselectivity and leads to the formation of (2-hydroxypropyl)triphenylphosphonium triflates 3 substituted in the 3-position with an alkoxy, alkylcarboxyl group, or halogen, which were isolated in a high yield. Using the methodology for the disclosure of epichlorohydrin with alcohols in the presence of boron trifluoride ether-ate, followed by the substitution of iodine for chlorine and treatment with triphenylphosphine, 2-hydroxypropyltriphenylphosphonium iodides 4 were also obtained. The molecular and supramolec-ular structure of the obtained phosphonium salts was established, and their high antitumor activity was revealed in relation to duodenal adenocarcinoma. The formation of liposomal systems based on phosphonium salt 3 and L-α-phosphatidylcholine (PC) was employed for improving the bioavailabil-ity and reducing the toxicity. They were produced by the thin film rehydration method and exhibited cytotoxic properties. This rational design of phosphonium salts 3 and 4 has promising potential of new vectors for targeted delivery into mitochondria of tumor cells.

Preparation and properties of phosphate surfactants containing ether and hydroxy groups

Phosphate surfactants containing ether and hydroxyl groups were prepared by a simple reaction between the corresponding epoxide and the diethyl phosphate. The relationships between the structure and colloidal properties were evaluated in terms of the critical micelle concentration (CMC), γCMC, foaming ability, and water absorbing and holding abilities. Based on these results, it was concluded that the ether and hydroxy groups synergistically worked together to decrease the CMC and increase the foaming ability. The degree of neutralization remarkably affected the colloidal properties. The highly neutralized states showed a more positive effect on water holding power but an opposite effect on the foaming ability. Copyright

The kinetics of chloromethyloxirane reaction with alcohols and their adducts in the presence of stannic chloride

Rate constants of the reaction of chloromethyloxirane (epichlorohydrin) with methyl, n-propyl, isopropyl, n-, sec-, tert-butyl, n-hexyl, n-octyl, and n-decyl alcohols in the presence of stannic chloride were studied at 30, 40, and 50°C. Reaction is not first order in respect to epichlorohydrine and is particularly fast at the beginning and its rate constants are proportional to the concentration of the catalyst. The rate constants increase in the homologous series of C1-C10 alcohols. The reaction rates of 2-chloromethyloxirane with 1-chloromethyl-2-alkoxyethanols are ca. 2.5-times larger than that with corresponding alcohols.