18386-03-3

Basic information

• Product Name: 3-(3-BROMO-PHENOXY)-PROPIONIC ACID
• Synonyms: Propionicacid, 3-(m-bromophenoxy)- (8CI); 3-(3-Bromophenoxy)propanoic acid
• CAS NO: 18386-03-3
• Molecular Formula: C₉H₉BrO₃
• Molecular Weight: 245.07
• Mol File: 18386-03-3.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 321.4°Cat760mmHg
• Flash Point: 148.2°C
• Appearance: /
• Density: 1.558g/cm³
• Vapor Pressure: 0.000123mmHg at 25°C
• Refractive Index: 1.568
• CAS DataBase Reference: 3-(3-BROMO-PHENOXY)-PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-BROMO-PHENOXY)-PROPIONIC ACID(18386-03-3)
• EPA Substance Registry System: 3-(3-BROMO-PHENOXY)-PROPIONIC ACID(18386-03-3)

Safety Data

• Hazardous Substances Data: 18386-03-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H9BrO3/c10-7-2-1-3-8(6-7)13-5-4-9(11)12/h1-3,6H,4-5H2,(H,11,12)

Upstream product

• 590-92-1 3-Bromopropionic acid 
• 591-20-8 3-Bromophenol 
• 1016736-70-1 3-(3-bromophenoxy)propanenitrile 
• 57-57-8 β-Propiolactone 
• 92584-63-9 3-(3-bromophenoxy)propan-1-ol 
• 107-94-8 chloropropionic acid 

Downstream Products

• 18442-22-3 7-Bromo-2,3-dihydro-4H-chromen-4-one 
• 168759-60-2 7-bromo-4H-benzopyran-4-one 
• 1260485-23-1 5-bromochromone 
• 1199782-67-6 5-bromo-4-chromanone 
• 129789-91-9 3-(3-bromo-phenoxy)-propionic acid ethyl ester 
• 1429323-80-7 C₁₇H₂₅BO₅ 
• 1429323-81-8 C₃₄H₄₇N₅O₉ 
• 1429323-82-9 C₁₇H₁₉N₅O₃ 

Relevant articles and documents

HISTONE ACETYLTRANSFERASE (HAT) INHIBITOR AND USE THEREOF

The present invention relates to a histone acetyltransferase (HAT) inhibitor. Provided are a compound represented by general formula I, a pharmaceutically acceptable salt, a stereoisomer, an enantiomer, a diastereomer, an atropisomer, a racemate, a polymorph, a solvate or an isotope-labeled compound (including deuterium substitution) thereof, a preparation method therefor, a pharmaceutical composition comprising the same, and use thereof in the treatment of various HAT-related diseases or conditions.

Biphenyl compound as well as preparation method and medical application thereof

The invention discloses a biphenyl compound as well as a preparation method and medical application thereof, the structure of the biphenyl compound is shown as a formula (I) or a formula (II), and thebiphenyl compound or pharmaceutically acceptable salt, tautomer, meso-isomer, raceme, stereoisomer, metabolite, metabolite precursor, prodrug or solvate thereof is a PD-L1 inhibitor. The compound hasa remarkable inhibiting effect on the interaction of PD-1 and PD-L1 protein, so that the compound can be applied to the preparation of PD-L1 inhibitors and immunomodulator drugs for preventing or treating tumors, autoimmune diseases, organ transplant rejection, infectious diseases and inflammatory diseases.

ARYL SULFONAMIDES AS BLT1 ANTAGONISTS

Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are antagonists of leukotriene B4 receptor 1 (BLT1) and may be useful in the treatment, prevention and suppression of diseases mediated by the leu