183968-59-4Relevant articles and documents
Stereocontrolled synthesis of syn- and anti-diol epoxide metabolites of triphenylene
Koreeda, Masato,Gopalaswamy, Ramesh,Yang, Jinhai,Tuinman, Roeland J.
, p. 8267 - 8270 (2007/10/03)
The synthesis of both syn- and anti-diol epoxide metabolites of triphenylene has been achieved under complete stereochemical control commencing with commercially available 9-phenanthrol in 18% (9 steps) and 37% (8 steps) overall yields, respectively. The exceptionally high stereoselectivity of the dimethyldioxirane oxidation of trans-dihydrodiol having the quasi-diaxially disposed hydroxyl groups is particularly noteworthy.