18412-15-2Relevant articles and documents
Synthesis and Conformational Analysis of 2,11-Disila[3.3]metacyclophanes
Hayamizu, Tomoo,Maeda, Hajime,Ouchi, Takashi,Kakiuchi, Naoki,Mizuno, Kazuhiko
, p. 3934 - 3938 (2016)
Silyl-tethered [3.3]metacyclophanes were prepared and subjected to conformational analysis. The results show that these compounds exist in unprecedented anti-rich metacyclophane forms. In the case of 2,2,11,11-tetrasubstituted 2,11-disila[3.3]metacyclopha
Ni(0)-Catalyzed Cross Coupling of Aryl O-Carbamates and Aryl Triflates with Grignard Reagents. Directed Ortho Metalation-Aligned Synthetic Methods for Polysubstituted Aromatics via a 1,2-Dipole Equivalent
Sengupta, Saumitra,Leite, Magda,Raslan, Delio Soares,Quesnelle, Claude,Snieckus, Victor
, p. 4066 - 4068 (2007/10/02)
The first Ni(0)-catalyzed cross-coupling reactions of aryl O-carbamates and aryl triflates with Grignard reagents (Scheme I) to give diversely polysubstituted aromatics 2d and 2e (Table I) which feature regiospecificity based on directed ortho metalation (carbamate), minimal β-hydride elimination (triflate), and dependence on steric and electronic effects are described.
The Metallation-Elimination Reaction, II. Monocyclic Anions and Polyanions
Wilhelm, Dieter,Clark, Timothy,Friedl, Thomas,Schleyer, Paul von Rague
, p. 751 - 760 (2007/10/02)
Equimolar mixtures of n-butyllithium and potassium tert-amyloxide effect metallation and metal hydride elimination of cyclic olefins directly to give conjugated anions and polyanions in a single operation. 1-Methyl-1-cycloalkenes or methylenecycloalkanes are particularly well suited and give highly unsaturated products.Odd-membered rings eliminate better than their even-membered counterparts, and eight-membered rings eliminate particularly slowly.Reactions with methyl iodide and trimethylsilyl chloride proceed smoothly in high yield.